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小肠非创伤性穿孔的管理见解。

Insight into the management of non-traumatic perforation of the small intestine.

作者信息

Jain Bhupendra Kumar, Arora Himanshu, Srivastava Upendra Kumar, Mohanty Debajyoti, Garg Pankaj Kumar

机构信息

University College of Medical Sciences and GTB Hospital, University of Delhi, New Delhi, India.

出版信息

J Infect Dev Ctries. 2010 Oct 28;4(10):650-4. doi: 10.3855/jidc.829.

Abstract

INTRODUCTION

Management of non-traumatic perforation of the small intestine has always been a consideration for surgeons because of associated enormous morbidity and mortality. There is a paucity of data on the management of non-traumatic perforation of the small intestine.

METHODOLOGY

A retrospective study was conducted which involved analysis of 192 patients treated for non-traumatic perforation of small intestine in a tertiary care teaching hospital in North India. The clinical profile and management of the patients were studied.

RESULTS

The most common cause of non-traumatic perforation of small intestine was typhoid (46.4%), followed by non-specific inflammation (39.2%), tuberculosis (12.8%) and malignant neoplasm (1.6%). Primary repair was the most frequent procedure (44.0%), followed by ileostomy (25.5%) and resection-anastomosis (19.3%). Superficial wound infection was the most frequent postoperative complication (46.8%), followed by wound dehiscence (31.3%). The wound infection rate was reduced significantly following delayed primary closure of skin incision. Enterocutaneous fistula/leak developed in 11.5% patients. Salvage ileostomy for post-operative intestinal leak resulted in a better survival rate as compared to conservative treatment (85.7% vs. 50.0%). The overall mortality rate was 16.6%.

CONCLUSION

Operative procedures undertaken for the management of non-traumatic perforation of small intestine can be classified into two groups: procedures that leave an intestinal suture line inside the peritoneal cavity and procedures that do not. The no suture line-in procedure seems to be better option in adverse patient conditions.

摘要

引言

由于小肠非创伤性穿孔会带来极高的发病率和死亡率,因此一直是外科医生需要考虑的问题。目前关于小肠非创伤性穿孔治疗的数据较少。

方法

进行了一项回顾性研究,分析了印度北部一家三级护理教学医院收治的192例小肠非创伤性穿孔患者。对患者的临床特征和治疗方法进行了研究。

结果

小肠非创伤性穿孔最常见的原因是伤寒(46.4%),其次是非特异性炎症(39.2%)、结核病(12.8%)和恶性肿瘤(1.6%)。一期修复是最常用的手术方式(44.0%),其次是回肠造口术(25.5%)和切除吻合术(19.3%)。浅表伤口感染是最常见的术后并发症(46.8%),其次是伤口裂开(31.3%)。皮肤切口延迟一期缝合后伤口感染率显著降低。11.5%的患者发生肠皮肤瘘/渗漏。与保守治疗相比,术后肠漏行挽救性回肠造口术的生存率更高(85.7%对50.0%)。总死亡率为16.6%。

结论

用于治疗小肠非创伤性穿孔的手术方法可分为两类:在腹腔内留下肠缝合线的手术方法和不留下的手术方法。在患者情况不利时,不留下缝合线的手术方法似乎是更好的选择。

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