Masrouha K Z, Anderson D D, Thomas T P, Kuhl L L, Brown T D, Marsh J L
Department of Orthopaedics and Rehabilitation, The University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA.
Iowa Orthop J. 2010;30:47-54.
Novel biomechanical methods have been developed to objectively measure acute fracture severity (from inter-fragmentary surface area) and chronic contact stress challenge (from patient-specific finite element analysis) in articular fractures. These new methods help clarify the pathomechanics of the development of post-traumatic osteoarthritis, and can contribute directly to the clinical care of patients. In this manuscript, the value of these two new measures is demonstrated in three illustrative tibial plafond fracture cases, in which both metrics are correlated with cartilage status and with patient outcomes at a minimum of two years after injury. These clinical cases demonstrate the utility of new biomechanical variables to advance clinical research and patient care, by providing a basis to predict outcome and select treatment.
已经开发出了新的生物力学方法，用于客观测量关节骨折的急性骨折严重程度（根据骨折碎片间表面积）和慢性接触应力挑战（根据患者特异性有限元分析）。这些新方法有助于阐明创伤后骨关节炎发展的病理力学，并能直接为患者的临床护理提供帮助。在本手稿中，通过三个具有代表性的胫骨平台骨折病例展示了这两种新测量方法的价值，在这些病例中，这两个指标均与软骨状态以及受伤后至少两年的患者预后相关。这些临床病例通过提供预测预后和选择治疗的依据，证明了新生物力学变量在推进临床研究和患者护理方面的实用性。
