Department of Obstetrics and Gynecology, Mansoura University, Mansoura, Egypt.
Arch Gynecol Obstet. 2011 Sep;284(3):671-5. doi: 10.1007/s00404-010-1744-2. Epub 2010 Nov 3.
To assess the efficacy of a modified Foley's catheter endometrial ablation in the treatment of abnormal uterine bleeding in low resource settings.
Four hundred and thirty premenopausal women with abnormal uterine bleeding were subjected to thermal balloon endometrial ablation using modified Foley's catheter. The primary outcome measure was patient satisfaction regarding menstrual blood loss. Secondary measures included improvement in quality of life scores and failure rates.
Three hundred and three patients were available for evaluation at 3-year follow up. 270/303 (89.1%) reported their satisfaction as indicated by reduction in days of menstrual flow per cycle (4.2 vs. 8.8 days, p < 0.0001). There was a significant improvement in quality of life scores (p < 0.0001). The rate of failure varies according to the interval of follow up from 15.6% at 6 months to 10.9% at 3 years.
Modified Foley's catheter endometrial ablation is a cost effective alternative to other thermal endometrial ablation techniques in the treatment of abnormal uterine bleeding in low resource settings.
评估改良 Foley 氏导管子宫内膜消融术在资源匮乏环境下治疗异常子宫出血的疗效。
对 430 例有异常子宫出血的绝经前妇女进行改良 Foley 氏导管热球子宫内膜消融术。主要观察指标为患者对月经出血量的满意度。次要观察指标包括生活质量评分的改善和失败率。
3 年随访时,303 例患者可进行评估。270/303(89.1%)例患者报告称,月经周期的天数(4.2 天比 8.8 天,p<0.0001)减少,表明他们的满意度有所提高。生活质量评分有显著改善(p<0.0001)。失败率随随访时间而变化,6 个月时为 15.6%,3 年时为 10.9%。
在资源匮乏环境下,改良 Foley 氏导管子宫内膜消融术是治疗异常子宫出血的一种经济有效的替代其他热子宫内膜消融技术的方法。