脱细胞真皮基质联合自体薄断层皮片移植的组织学分析及长期效果
[Histologic analysis and long-term effect of acellular dermal matrix combined with autologous thin split-thickness skin graft].
作者信息
Han Li-Hui, Lü Ren-Rong, Huo Ran, Yuan Dong-Liang, Guo Xuan
机构信息
Department of Burn and Plastic Surgery, Shandong Province Hospital, Jinan 250012, China.
出版信息
Zhonghua Zheng Xing Wai Ke Za Zhi. 2010 Jul;26(4):272-4.
OBJECTIVE
To evaluate the long-term therapeutic effect and histologic result of ADM combined with autologous thin split-thickness skin graft.
METHODS
23 patients were treated with acellular dermal matrix (ADM) combined with autologous thin split-thickness skin graft. The patients were followed up at 3, 6, 12, and 18 months after operation. The histological analysis was also performed.
RESULTS
3, 6, 12, 18 months after operation, the composite skin grafts became smooth with no hypertrophic scar and hyperpigmentation. It was soft and elastic. The joints could move randomly. The histologic study showed the composite skin graft had a similar appearance as the normal skin.
CONCLUSION
As for the treatment of wound, the composite skin graft with ADM is smooth and soft with good elasticity after transplantation, but it has no perspiration.
目的
评估脱细胞真皮基质（ADM）联合自体薄断层皮片移植的长期治疗效果及组织学结果。
方法
23例患者接受脱细胞真皮基质联合自体薄断层皮片移植治疗。术后3、6、12和18个月对患者进行随访，并进行组织学分析。
结果
术后3、6、12、18个月，复合皮片变得光滑，无肥厚性瘢痕和色素沉着。其柔软且有弹性。关节可随意活动。组织学研究显示复合皮片外观与正常皮肤相似。
结论
对于创面治疗，ADM复合皮片移植后光滑、柔软，弹性良好，但无排汗功能。
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