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脱细胞真皮基质联合自体薄断层皮片移植的组织学分析及长期效果

[Histologic analysis and long-term effect of acellular dermal matrix combined with autologous thin split-thickness skin graft].

作者信息

Han Li-Hui, Lü Ren-Rong, Huo Ran, Yuan Dong-Liang, Guo Xuan

机构信息

Department of Burn and Plastic Surgery, Shandong Province Hospital, Jinan 250012, China.

出版信息

Zhonghua Zheng Xing Wai Ke Za Zhi. 2010 Jul;26(4):272-4.

PMID:21046774
Abstract

OBJECTIVE

To evaluate the long-term therapeutic effect and histologic result of ADM combined with autologous thin split-thickness skin graft.

METHODS

23 patients were treated with acellular dermal matrix (ADM) combined with autologous thin split-thickness skin graft. The patients were followed up at 3, 6, 12, and 18 months after operation. The histological analysis was also performed.

RESULTS

3, 6, 12, 18 months after operation, the composite skin grafts became smooth with no hypertrophic scar and hyperpigmentation. It was soft and elastic. The joints could move randomly. The histologic study showed the composite skin graft had a similar appearance as the normal skin.

CONCLUSION

As for the treatment of wound, the composite skin graft with ADM is smooth and soft with good elasticity after transplantation, but it has no perspiration.

摘要

目的

评估脱细胞真皮基质(ADM)联合自体薄断层皮片移植的长期治疗效果及组织学结果。

方法

23例患者接受脱细胞真皮基质联合自体薄断层皮片移植治疗。术后3、6、12和18个月对患者进行随访,并进行组织学分析。

结果

术后3、6、12、18个月,复合皮片变得光滑,无肥厚性瘢痕和色素沉着。其柔软且有弹性。关节可随意活动。组织学研究显示复合皮片外观与正常皮肤相似。

结论

对于创面治疗,ADM复合皮片移植后光滑、柔软,弹性良好,但无排汗功能。

相似文献

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[Histologic analysis and long-term effect of acellular dermal matrix combined with autologous thin split-thickness skin graft].脱细胞真皮基质联合自体薄断层皮片移植的组织学分析及长期效果
Zhonghua Zheng Xing Wai Ke Za Zhi. 2010 Jul;26(4):272-4.
2
[Clinical application and long-term follow-up study of acellular dermal matrix combined with auto-skin grafting].脱细胞真皮基质联合自体皮移植的临床应用及长期随访研究
Zhonghua Shao Shang Za Zhi. 2008 Feb;24(1):26-9.
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Zhonghua Shao Shang Za Zhi. 2010 Dec;26(6):439-43.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2005 Feb;17(2):92-4.
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[Application of meshed acellular dermis xenograft (pigskin) with scalp thin skin autograft in 15 patients].网状脱细胞真皮异种移植物(猪皮)联合自体头皮薄皮移植在15例患者中的应用
Zhonghua Zheng Xing Wai Ke Za Zhi. 2002 Sep;18(5):273-5.