新型吲哚基杂环化合物的合成及其抗病毒活性
Synthesis and antiviral activity of new indole-based heterocycles.
作者信息
Abdel-Gawad Hassan, Mohamed Hanan Ahmed, Dawood Kamal Mohamed, Badria Farid Abdel-Rahem
机构信息
Applied Organic Chemistry Department, National Research Centre, Egypt.
出版信息
Chem Pharm Bull (Tokyo). 2010 Nov;58(11):1529-31. doi: 10.1248/cpb.58.1529.
PMID:21048349
Abstract
New 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine and 1,3-thiazole derivatives incorporating indole nucleus were prepared using 3-acetylindole as precursor and evaluated for their antiviral activity against herpes simplex type 1 (HSV-1).
摘要
以3-乙酰基吲哚为前体，制备了含吲哚核的新型1,2,4-三唑并[3,4-b]-1,3,4-噻二嗪和1,3-噻唑衍生物，并对其抗1型单纯疱疹病毒（HSV-1）的抗病毒活性进行了评估。
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