Carlsson Jessica Mariana, Olsen Dorte Reff, Kastrup Marianne, Mortensen Erik Lykke
The Mental Health Services, Capital Region of Denmark, Psychiatric Centre Amager, Copenhagen K, Denmark.
J Nerv Ment Dis. 2010 Nov;198(11):824-8. doi: 10.1097/NMD.0b013e3181f97be3.
The aim of this study was to examine long-term changes in symptoms of post-traumatic stress disorder, depression, anxiety, and in health-related quality of life in traumatized refugees 23 months after admission to multidisciplinary treatment. The study group comprised 45 persons admitted to the Rehabilitation and Research Centre for Torture Victims in 2001 to 2002. Data on background, trauma, present social situation, mental symptoms (Hopkins Symptom Checklist-25, Hamilton Depression Scale, Harvard Trauma Questionnaire), and on health-related quality of life (World Health Organization Quality of Life-Bref) were collected before treatment and after 9 and 23 months. No substantial changes in mental health were observed at the 9-month follow-up, and the minor decrease in some symptoms observed between the 9 and 23 months may reflect regression toward the mean or the natural course of symptoms in this cohort. Thus, no clinically significant improvement was observed, but there is a need for further studies, in particular randomized trials evaluating the efficacy of various health-related and social interventions among severely traumatized refugees.
本研究的目的是调查遭受创伤的难民在接受多学科治疗23个月后创伤后应激障碍、抑郁、焦虑症状以及健康相关生活质量的长期变化。研究组由2001年至2002年入住酷刑受害者康复与研究中心的45人组成。收集了治疗前、治疗9个月后和23个月后的背景、创伤、当前社会状况、精神症状（霍普金斯症状清单-25、汉密尔顿抑郁量表、哈佛创伤问卷）以及健康相关生活质量（世界卫生组织生活质量简表）的数据。在9个月的随访中未观察到心理健康有实质性变化，9个月至23个月期间观察到的某些症状的轻微下降可能反映了该队列中症状向均值的回归或自然病程。因此，未观察到临床上有显著改善，但需要进一步研究，特别是评估各种健康相关和社会干预措施对严重创伤难民疗效的随机试验。
