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Doxorubicin pathways: pharmacodynamics and adverse effects.

作者信息

Thorn Caroline F, Oshiro Connie, Marsh Sharon, Hernandez-Boussard Tina, McLeod Howard, Klein Teri E, Altman Russ B

机构信息

Departments of Genetics, Stanford University Medical Center, California 94305-5120, USA.

出版信息

Pharmacogenet Genomics. 2011 Jul;21(7):440-6. doi: 10.1097/FPC.0b013e32833ffb56.

DOI:10.1097/FPC.0b013e32833ffb56
PMID:21048526
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3116111/
Abstract
摘要

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本文引用的文献

1
Different anthracycline derivates for reducing cardiotoxicity in cancer patients.用于降低癌症患者心脏毒性的不同蒽环类衍生物。
Cochrane Database Syst Rev. 2010 May 12;2010(5):CD005006. doi: 10.1002/14651858.CD005006.pub4.
2
Pharmacogenetics of target genes across doxorubicin disposition pathway: a review.多柔比星处置途径中靶基因的药物遗传学：综述。
Curr Drug Metab. 2010 Jan;11(1):115-28. doi: 10.2174/138920010791110890.
3
Naturally occurring variants of human CBR3 alter anthracycline in vitro metabolism.人类 CBR3 的自然发生变体改变蒽环类药物的体外代谢。
J Pharmacol Exp Ther. 2010 Mar;332(3):755-63. doi: 10.1124/jpet.109.160614. Epub 2009 Dec 9.
4
Influence of the polymorphism in candidate genes on late cardiac damage in patients treated due to acute leukemia in childhood.候选基因多态性对儿童急性白血病治疗后晚期心脏损害的影响。
Leuk Lymphoma. 2009 Oct;50(10):1693-8. doi: 10.1080/10428190903177212.
5
The role of topoisomerase IIalpha and HER-2 in predicting sensitivity to anthracyclines in breast cancer patients.拓扑异构酶IIα和HER-2在预测乳腺癌患者对蒽环类药物敏感性中的作用。
Cancer Treat Rev. 2009 Dec;35(8):662-7. doi: 10.1016/j.ctrv.2009.08.006. Epub 2009 Sep 15.
6
Nitric oxide synthase variants and disease-free survival among treated and untreated breast cancer patients in a Southwest Oncology Group clinical trial.西南肿瘤协作组一项临床试验中，一氧化氮合酶变体与接受治疗和未接受治疗的乳腺癌患者的无病生存期
Clin Cancer Res. 2009 Aug 15;15(16):5258-66. doi: 10.1158/1078-0432.CCR-09-0685. Epub 2009 Aug 11.
7
Rlip76 transports sunitinib and sorafenib and mediates drug resistance in kidney cancer.Rlip76 转运舒尼替尼和索拉非尼，并介导肾癌的耐药性。
Int J Cancer. 2010 Mar 15;126(6):1327-38. doi: 10.1002/ijc.24767.
8
Doxorubicin: the good, the bad and the ugly effect.多柔比星：好的、坏的和丑陋的影响。
Curr Med Chem. 2009;16(25):3267-85. doi: 10.2174/092986709788803312. Epub 2009 Sep 1.
9
Analysis of the host pharmacogenetic background for prediction of outcome and toxicity in diffuse large B-cell lymphoma treated with R-CHOP21.分析宿主药物遗传学背景以预测接受R-CHOP21治疗的弥漫性大B细胞淋巴瘤的结局和毒性。
Leukemia. 2009 Jun;23(6):1118-26. doi: 10.1038/leu.2008.398. Epub 2009 Jan 29.
10
New developments in anthracycline-induced cardiotoxicity.蒽环类药物所致心脏毒性的新进展
Curr Med Chem. 2009;16(13):1656-72. doi: 10.2174/092986709788186228.