Algahtani Hussein, Moulin Dwight E, Bolton Charles F, Abulaban Ahmad A
Department of Medicine, King Abdulaziz Medical City, PO Box 12723, Jeddah 21483, Kingdom of Saudi Arabia, Tel. +966 (2) 6240000. Ext. 21298, 22070. Fax. +966 (2) 6240000. Ext. 22765. E-mail:
Neurosciences (Riyadh). 2009 Oct;14(4):374-8.
Weakness of limb and respiratory muscles developing in the course of treatment in the intensive care unit (ICU) is commonly due to critical illness polyneuropathy, a complication of sepsis, or critical illness myopathy, a complication of the use of neuromuscular blocking agents and steroids. Guillain-Barre syndrome may rarely occur in this setting. We report 2 patients identified in our ICU in the last 20 years. Surgery was an apparent precipitating event in both patients. The clinical, electrophysiological, and cerebrospinal fluid features were consistent with this diagnosis. Both patients responded to treatment; the first case was treated with plasmapheresis while the other with intravenous immune globulin. Thus, while rare, it is important to identify this disorder in the ICU because of its response to specific treatment.
在重症监护病房（ICU）治疗过程中出现的肢体和呼吸肌无力通常归因于危重病性多发性神经病（败血症的一种并发症）或危重病性肌病（使用神经肌肉阻滞剂和类固醇的一种并发症）。格林-巴利综合征在这种情况下很少发生。我们报告了过去20年在我们ICU中确诊的2例患者。手术在这两名患者中均为明显的诱发事件。临床、电生理和脑脊液特征均与该诊断相符。两名患者均对治疗有反应；第一例接受了血浆置换治疗，另一例接受了静脉注射免疫球蛋白治疗。因此，虽然罕见，但在ICU中识别这种疾病很重要，因为它对特定治疗有反应。
