Division of Gastroenterology and Hepatology, Mayo Clinic Arizona, Scottsdale, Arizona 85259, USA.
Am J Gastroenterol. 2010 Nov;105(11):2318-22. doi: 10.1038/ajg.2010.235.
Afternoon colonoscopies have higher failure rates, due primarily to poor bowel cleansing. Hypothesizing that the time of administration influences the quality of bowel cleansing, we compared the quality of bowel cleansing for afternoon colonoscopies in patients completing the preparation on the same day vs. the day before colonoscopy.
Data on afternoon colonoscopies performed between July 2008 and April 2009 were obtained from our endoscopy database. Bowel-preparation options were 4L polyethylene glycol (PEG) or 2L PEG plus four bisacodyl tablets. Patients could take the preparation on the same day as the procedure or the day prior, or consume half the day prior and half the same day. Bowel-cleansing quality was reported as excellent, good, fair-adequate, inadequate, or poor. Multivariate logistic regression analysis evaluated the association between quality of bowel cleansing and time of preparation administration.
Bowel cleansing was reported as poor or inadequate in 7% of patients, adequate in 63%, and good or excellent in 30%. Afternoon colonoscopies using the same-day 4L PEG preparation were 3.14 times more likely to have fair-adequate cleansing and 7.03 times more likely to have good or excellent cleansing when compared with the other options.
Same-day 4L PEG preparation for afternoon colonoscopy confers better-quality cleansing than prior-day preparation.
下午行结肠镜检查时，由于肠道准备不佳，其失败率较高。我们推测给药时间可能会影响肠道清洁的质量，因此比较了同一天和结肠镜检查前一天完成肠道准备的下午行结肠镜检查患者的肠道清洁质量。
我们从内镜数据库中获取了 2008 年 7 月至 2009 年 4 月期间行下午结肠镜检查患者的数据。肠道准备方案为 4L 聚乙二醇（PEG）或 2L PEG 加 4 片双八面体蒙脱石散。患者可在检查当天或前一天服用准备药物，也可前一天服用一半，当天服用另一半。肠道清洁质量报告为优、良、中-可、差或差。多变量逻辑回归分析评估了肠道清洁质量与准备给药时间之间的关系。
7%的患者肠道清洁被报告为差或不足，63%的患者肠道清洁为可，30%的患者肠道清洁为优或良。与其他方案相比，同日给予 4L PEG 方案的下午结肠镜检查患者的中-可清洁率高 3.14 倍，优或良清洁率高 7.03 倍。
同日 4L PEG 方案用于下午结肠镜检查可提供更好的肠道清洁质量。
