Luzny Jan, Valihrachova Sylva, Novak Jaroslav, Zapletal Tomas, Donek Emanuel, Arogunmati Olubunmi
Department of Social Medicine and Health Policy, Palacky University Olomouc, Czech Republic.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2010 Sep;154(3):261-4. doi: 10.5507/bp.2010.040.
Ileus states are serious conditions that may lead to pathophysiological changes which in turn can result in perforation of bowel, peritonitis, sepsis or death. Our paper discusses paralytic ileus states, which can be caused by psychopharmaceutics with anticholinergic side effects.
Retrospective analysis of cases of paralytic ileus in mentally ill patients admitted to Mental Hospital Kromeriz.
Although some old psychopharmacs have a much higher potential for anticholinergic side effects than the new ones, there are still some of the new modern antipsychotics which also have anticholinergic side effects which could cause paralytic ileus. Both psychiatrists and surgeons should pay attention to atypical or changed signs of ileus states in mentally ill patients and should be aware of the confounding factors which could make the diagnosis of ileus difficult in mentally ill patients.
肠梗阻状态是严重的病症,可能导致病理生理变化,进而可能导致肠穿孔、腹膜炎、败血症或死亡。我们的论文讨论了麻痹性肠梗阻状态,其可能由具有抗胆碱能副作用的精神药物引起。
对克罗梅日什精神病院收治的精神病患者麻痹性肠梗阻病例进行回顾性分析。
尽管一些旧的精神药物比新的精神药物具有更高的抗胆碱能副作用潜力,但仍有一些新型现代抗精神病药物也具有抗胆碱能副作用,可能导致麻痹性肠梗阻。精神科医生和外科医生都应注意精神病患者肠梗阻状态的非典型或变化迹象,并应意识到可能使精神病患者肠梗阻诊断困难的混杂因素。