纳米结构引发质谱代谢物分析和成像。
Nanostructure-initiator mass spectrometry metabolite analysis and imaging.
机构信息
Center for Metabolomics and Mass Spectrometry, Department of Chemistry, The Scripps Research Institute.
出版信息
Anal Chem. 2011 Jan 1;83(1):2-7. doi: 10.1021/ac101565f. Epub 2010 Nov 4.
Abstract
Nanostructure-Initiator Mass Spectrometry (NIMS) is a matrix-free desorption/ionization approach that is particularly well-suited for unbiased (untargeted) metabolomics. An overview of the NIMS technology and its application in the detection of biofluid and tissue metabolites are presented. (To listen to a podcast about this feature, please go to the Analytical Chemistry multimedia page at pubs.acs.org/page/ancham/audio/index.html .).
摘要
纳米结构引发质谱法 (NIMS) 是一种无基质解吸/电离方法，特别适合于无偏向（非靶向）代谢组学。本文概述了 NIMS 技术及其在生物流体和组织代谢物检测中的应用。（要收听有关此功能的播客，请访问 pubs.acs.org/page/ancham/audio/index.html 的分析化学多媒体页面。）。
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