Suppr超能文献

步态速度是老年心脏手术患者死亡率和主要发病率的增量预测指标。

Gait speed as an incremental predictor of mortality and major morbidity in elderly patients undergoing cardiac surgery.

机构信息

Division of Cardiology, Department of Medicine, SMBD-Jewish General Hospital, McGill University, Montreal, Quebec, Canada.

出版信息

J Am Coll Cardiol. 2010 Nov 9;56(20):1668-76. doi: 10.1016/j.jacc.2010.06.039.

Abstract

OBJECTIVES

The purpose of this study was to test the value of gait speed, a clinical marker for frailty, to improve the prediction of mortality and major morbidity in elderly patients undergoing cardiac surgery.

BACKGROUND

It is increasingly difficult to predict the elderly patient's risk posed by cardiac surgery because existing risk assessment tools are incomplete.

METHODS

A multicenter prospective cohort of elderly patients undergoing cardiac surgery was assembled at 4 tertiary care hospitals between 2008 and 2009. Patients were eligible if they were 70 years of age or older and were scheduled for coronary artery bypass and/or valve replacement or repair. The primary predictor was slow gait speed, defined as a time taken to walk 5 m of ≥ 6 s. The primary end point was a composite of in-hospital post-operative mortality or major morbidity.

RESULTS

The cohort consisted of 131 patients with a mean age of 75.8 ± 4.4 years; 34% were female patients. Sixty patients (46%) were classified as slow walkers before cardiac surgery. Slow walkers were more likely to be female (43% vs. 25%, p = 0.03) and diabetic (50% vs. 28%, p = 0.01). Thirty patients (23%) experienced the primary composite end point of mortality or major morbidity after cardiac surgery. Slow gait speed was an independent predictor of the composite end point after adjusting for the Society of Thoracic Surgeons risk score (odds ratio: 3.05; 95% confidence interval: 1.23 to 7.54).

CONCLUSIONS

Gait speed is a simple and effective test that may identify a subset of vulnerable elderly patients at incrementally higher risk of mortality and major morbidity after cardiac surgery.

摘要

目的

本研究旨在检验步态速度(衰弱的临床标志物)在预测行心脏手术的老年患者的死亡率和主要发病率方面的价值。

背景

由于现有的风险评估工具不完整,因此越来越难以预测老年患者心脏手术带来的风险。

方法

在 2008 年至 2009 年间,在 4 家三级护理医院组建了一个接受心脏手术的老年患者多中心前瞻性队列。如果患者年龄在 70 岁或以上,计划进行冠状动脉旁路和/或瓣膜置换或修复手术,则符合入选条件。主要预测指标为步态缓慢,定义为行走 5 米的时间超过 6 秒。主要终点是住院术后死亡或主要发病率的复合终点。

结果

该队列包括 131 名平均年龄为 75.8 ± 4.4 岁的患者;34%为女性患者。60 名(46%)患者在心脏手术前被归类为步态缓慢者。在心脏手术后,步态缓慢者更有可能为女性(43%比 25%,p=0.03)和患有糖尿病(50%比 28%,p=0.01)。30 名(23%)患者在心脏手术后经历了死亡或主要发病率的主要复合终点。在调整胸外科医生协会风险评分后,步态缓慢是复合终点的独立预测因子(优势比:3.05;95%置信区间:1.23 至 7.54)。

结论

步态速度是一种简单有效的测试方法,它可以识别出一组脆弱的老年患者,他们在心脏手术后的死亡率和主要发病率方面的风险逐渐增加。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验