Elsner Ann E, Muller Matthew S
Indiana University School of Optometry Bloomington, IN, 47405, USA.
Laser Photon Rev. 2008 Oct 1;2(5):350-376. doi: 10.1002/lpor.200810015.
We review laser applications for primarily in vivo ocular imaging techniques, describing their constraints based on biological tissue properties, safety, and the performance of the imaging system. We discuss the need for cost effective sources with practical wavelength tuning capabilities for spectral studies. Techniques to probe the pathological changes of layers beneath the highly scattering retina and diagnose the onset of various eye diseases are described. The recent development of several optical coherence tomography based systems for functional ocular imaging is reviewed, as well as linear and nonlinear ocular imaging techniques performed with ultrafast lasers, emphasizing recent source developments and methods to enhance imaging contrast.
我们回顾了主要用于体内眼部成像技术的激光应用,基于生物组织特性、安全性和成像系统性能描述了它们的局限性。我们讨论了对于光谱研究而言,具备实用波长调谐能力的经济高效光源的需求。描述了探测高度散射视网膜下方各层病理变化以及诊断各种眼部疾病发病情况的技术。回顾了几种基于光学相干断层扫描的功能性眼部成像系统的最新进展,以及使用超快激光进行的线性和非线性眼部成像技术,重点介绍了近期的光源发展以及增强成像对比度的方法。