Davidson K G, Walbaum P R, McCormack R J
Thorax. 1978 Jun;33(3):359-67. doi: 10.1136/thx.33.3.359.
The experience of one regional thoracic surgical unit in managing intrathoracic neural tumours over a 25-year period is presented. Neural tumour was diagnosed in 55 patients, of whom 41 were asymptomatic. In 11 patients complete resection was not achieved--the reasons for this and its effect on the outcome of the patient are discussed. There were 52 posterior mediastinal and three lateral chest wall tumours. The pathological distribution was as follows--benign nerve sheath tumours (neurofibroma, neurilemoma) 39, ganglioneuroma 13, and neuroblastoma 3. One neurofibroma recurred as a neurosarcoma six years after its apparently complete resection and was removed by an extensive resection at reoperation. One neuroblastoma recurred within the spinal canal four years after incomplete excision at thoracotomy--this patient died subsequently of widespread metastatic neuroblastoma. No other tumour is known to have recurred.
本文介绍了一个地区性胸外科单位在25年期间管理胸内神经肿瘤的经验。55例患者被诊断为神经肿瘤,其中41例无症状。11例患者未实现完全切除,讨论了其原因及其对患者预后的影响。有52例后纵隔肿瘤和3例侧胸壁肿瘤。病理分布如下:良性神经鞘瘤(神经纤维瘤、神经鞘瘤)39例,神经节瘤13例,神经母细胞瘤3例。1例神经纤维瘤在看似完全切除6年后复发为神经肉瘤,并在再次手术时通过广泛切除将其切除。1例神经母细胞瘤在开胸不完全切除4年后在椎管内复发,该患者随后死于广泛转移的神经母细胞瘤。已知没有其他肿瘤复发。