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头颈部区域肺泡横纹肌肉瘤实性变型:头颈部细针穿刺门诊诊断困境的一例报告

Solid variant of alveolar rhabdomyosarcoma in the head and neck region: a case report of a diagnostic dilemma in a head and neck fine needle aspiration clinic.

作者信息

Aslam Muhammad B, Sahasrabudhe Neil, Kumar Santhi N, Shenjere Patrick, Belloso Antonio, Morar Pradeep

机构信息

Department of Histopathology, Royal Blackburn Hospital, Haslingden Road, Blackburn BB2 3HH, Lancashire, UK.

出版信息

Acta Cytol. 2010 Sep-Oct;54(5 Suppl):849-52.

PMID:21053554
Abstract

BACKGROUND

Alveolar rhabdomyosarcoma (ARMS) is one of the major categories of rhabdomyosarcomas; it encompasses malignant tumors of striated muscle and occurs more frequently in the extremities. It is uncommonly reported in young adults and extremely rarely found in middle-aged and elderly patients.

CASE

A 54-year-old man presented to a rapid head and neck clinic with a history of rapid enlargement of neck lumps on the right side of his neck over a period of 5 weeks. The diagnosis of an undifferentiated malignant small round cell tumor was made from cytologic examination of the aspirated sample, and biopsy of the lesion was advised. On histologic analysis, diagnosis of solid variant of ARMS was made.

CONCLUSION

A solid variant of ARMS in an older population has not been published in the literature within the settings of a rapid head and neck clinic. Therefore, the remote possibility of this diagnosis should be considered in the differential diagnosis of a malignant, round cell tumor in fine needle aspiration cytology in an older patient's neck lump.

摘要

背景

肺泡状横纹肌肉瘤(ARMS)是横纹肌肉瘤的主要类型之一;它包含横纹肌恶性肿瘤,且更常见于四肢。在年轻成年人中报道较少,在中老年患者中极为罕见。

病例

一名54岁男性因右侧颈部肿块在5周内迅速增大的病史就诊于头颈快速诊疗门诊。通过对抽吸样本的细胞学检查诊断为未分化恶性小圆形细胞肿瘤,并建议对病变进行活检。组织学分析确诊为ARMS实性变型。

结论

在头颈快速诊疗门诊的背景下,老年人群中ARMS实性变型在文献中尚未见报道。因此,在老年患者颈部肿块细针穿刺细胞学检查中,对恶性圆形细胞肿瘤进行鉴别诊断时应考虑到这种诊断的极小可能性。

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J Cytol. 2014 Jul;31(3):168-70. doi: 10.4103/0970-9371.145656.