Qiu Qian-hui, Liang Min-zhi, Liu Hui, Chen Shao-hua, Zhang Hong-bin, Zhang Qiu-hang
Department of Otorhinolaryngology, Guangdong General Hospital, Guangdong Academy of Medical Science, Guangzhou 510080, China.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2010 Jul;45(7):551-4.
To discuss the clinical characteristics and treatments for chondrosarcoma of paranasal sinus and the skull base.
The clinical characteristics of chondrosarcoma of paranasal sinus and skull base in 7 patients underwent endoscopic surgeries between 2001 and 2008 were analyzed. Of the patients, 4 men and 3 women. The patients' age ranged from 18 to 47 years, with a median of 31 years.
stuffy, nose bleeding, runny, headache, diplopia, eye outreach limited, blurred vision and even blindness. Surgery methods: under nasal endoscopy, after the attachment sites of the tumors to normal tissues were confirmed, the tumors were peeled off along the clear boundary between the tumors and normal tissues, and the potential residual tumor tissues on bones were cleared by a drill.
The patients were followed up postoperatively for 24 to 108 months, with a median of 36 months. Five of 7 patients were no recurrence, 2 were alive with tumor.
Chondrosarcoma of paranasal sinus and skull base can be treated by nasal endoscopic surgery, with good clinical outcome.
探讨鼻窦及颅底软骨肉瘤的临床特点及治疗方法。
分析2001年至2008年间7例行内镜手术的鼻窦及颅底软骨肉瘤患者的临床特点。患者中男性4例，女性3例。年龄18至47岁，中位年龄31岁。
鼻塞、鼻出血、流涕、头痛、复视、眼球外展受限、视力模糊甚至失明。手术方法：在鼻内镜下，确认肿瘤与正常组织的附着部位后，沿肿瘤与正常组织的清晰边界剥离肿瘤，并用钻头清除骨面上潜在的残留肿瘤组织。
患者术后随访24至108个月，中位随访时间36个月。7例患者中5例无复发，2例带瘤生存。
鼻窦及颅底软骨肉瘤可通过鼻内镜手术治疗，临床效果良好。
