Deng Bi-Yong, Cui Jian-Guo, Li Chun-Jian, Yu Rong-Bin, Guo Su-Wan, Yang Zhi-Jian, Cao Ke-Jiang, Huang Jun
Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2010 Aug;38(8):702-5.
To explore the prevalence and associated factors of anxiety and depression symptoms in hospitalized Chinese patients with coronary artery disease (CAD).
From June 2007 to May 2009, 1083 hospitalized patients with confirmed coronary artery disease were recruited in this study. The ZUNG Self-rating Anxiety Scale (SAS) and the ZUNG Self-rating Depression Scale (SDS) were used for the psychological assessment. Economic status, living condition and the environment of both living and working places were evaluated by epidemiological questionnaires.
The prevalence of pure anxiety, pure depression symptoms and the combination of anxiety and depression symptoms were 7.9%, 28.3% and 14.3% respectively. Incidence of anxiety and depression symptoms was significantly higher in female patients compared with in male patients (P = 0.003, 0.012 respectively) and in aged patients than in middle-aged patients (P = 0.001). The elderly, less than 9 years of education and poor sleep quality increased the risk of anxiety symptom with ORs of 1.63 (95%CI: 1.21 - 2.21), 1.54 (95%CI: 1.15 - 2.07) and 1.62 (95%CI: 1.34 - 1.96), respectively, while workplace noise, history of chronic disease and poor sleep quality increased the risk of depression symptom with ORs of 1.52 (95%CI: 1.18 - 1.98), 1.36 (95%CI: 1.06 - 1.75) and 1.27 (95%CI: 1.08 - 1.50), respectively. Female (OR = 1.91, 95%CI: 1.22-2.98), aged patient (OR = 1.84, 95%CI: 1.23 - 2.76), workplace noise (OR = 1.61, 95%CI: 1.07 - 2.42), history of chronic disease (OR = 1.84, 95%CI: 1.24 - 2.71) and poor sleep quality (OR = 1.73, 95%CI: 1.35 - 2.21) were significantly correlated with the combined incidence of anxiety and depression symptoms.
Around half of the Chinese hospitalized CAD patients were complicated with various degrees of anxiety and/or depression symptoms. Female and aged patients were at higher risk for anxiety and depression symptoms. Sleep quality, workplace noise, years of education and history of chronic disease were independent risk factors for anxiety or depression symptoms.
探讨中国住院冠心病（CAD）患者焦虑和抑郁症状的患病率及相关因素。
2007年6月至2009年5月，本研究招募了1083例确诊为冠心病的住院患者。采用zung自评焦虑量表（SAS）和zung自评抑郁量表（SDS）进行心理评估。通过流行病学调查问卷评估经济状况、生活条件以及生活和工作场所的环境。
单纯焦虑、单纯抑郁症状以及焦虑和抑郁症状合并出现的患病率分别为7.9%、28.3%和14.3%。女性患者焦虑和抑郁症状的发生率显著高于男性患者（分别为P = 0.003，0.012），老年患者高于中年患者（P = 0.001）。老年人、受教育年限不足9年以及睡眠质量差会增加焦虑症状的风险，其比值比分别为1.63（95%置信区间：1.21 - 2.21）、1.54（95%置信区间：1.15 - 2.07）和1.62（95%置信区间：1.34 - 1.96），而工作场所噪音、慢性病病史和睡眠质量差会增加抑郁症状的风险，其比值比分别为1.52（95%置信区间：1.18 - 1.98）、1.36（95%置信区间：1.06 - 1.75）和1.27（95%置信区间：1.08 - 1.50）。女性（比值比 = 1.91，95%置信区间：1.22 - 2.98）、老年患者（比值比 = 1.84，95%置信区间：1.23 - 2.76）、工作场所噪音（比值比 = 1.61，95%置信区间：1.07 - 2.42）、慢性病病史（比值比 = 1.84，95%置信区间：1.24 - 2.71）和睡眠质量差（比值比 = 1.73，95%置信区间：1.35 - 2.21）与焦虑和抑郁症状的合并发生率显著相关。
约一半的中国住院冠心病患者合并有不同程度的焦虑和/或抑郁症状。女性和老年患者出现焦虑和抑郁症状的风险更高。睡眠质量、工作场所噪音、受教育年限和慢性病病史是焦虑或抑郁症状的独立危险因素。
