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增强型气囊阴道成形术治疗雄激素不敏感综合征所致盲阴道

Enhancement balloon vaginoplasty for treatment of blind vagina due to androgen insensitivity syndrome.

机构信息

Women's Health University Center, Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt.

出版信息

Fertil Steril. 2011 Feb;95(2):779-82. doi: 10.1016/j.fertnstert.2010.10.008. Epub 2010 Nov 5.

Abstract

OBJECTIVE

To evaluate the safety and feasibility of enhancement balloon vaginoplasty (EBV) in cases with blind vagina due to androgen insensitivity syndrome.

DESIGN

Case series with description of the technique.

SETTING

Women's Health Center, Assiut University, and Sohage Teaching Hospital, Sohage University.

PATIENT(S): Three X,Y females (two cases presenting with apareunia and the third presenting with severe dyspareunia).

INTERVENTION(S): Laparoscopy-assisted EBV.

MAIN OUTCOME MEASURE(S): Operative time, complications, depth and width of neovagina, and functional status.

RESULT(S): Our cases were currently married phenotypical females and had 46,X,Y karyotypes. They had well developed secondary sexual characters, but they presented with failure of intravaginal intercourse. EBV was performed successfully for three X,Y females. The total operative time was 38-45 minutes. No operative complications were reported, and there were no reported postoperative complications as a result of moving the direction of traction. The resultant neovagina's depths were 10, 11, and 12 cm, respectively. Sexual intercourse was set off on the day of discharge. Penetration and satisfaction scores increased up to 90 points for both partners.

CONCLUSION(S): It was feasible and safe to move centrally the direction of traction and to move the point of catheter exit up with apparently better outcomes than conventional balloon vaginoplasty for treatment of blind vagina due to androgen insensitivity syndrome.

摘要

目的

评估增强型球囊阴道成形术(EBV)在雄激素不敏感综合征导致盲阴道病例中的安全性和可行性。

设计

病例系列,描述技术。

地点

阿西尤特大学妇女健康中心和索哈格教学医院,索哈格大学。

患者

3 名 X、Y 女性(2 例表现为性交困难,第 3 例表现为严重性交痛)。

干预措施

腹腔镜辅助 EBV。

主要观察指标

手术时间、并发症、新阴道的深度和宽度以及功能状态。

结果

我们的病例均为已婚表型女性,核型为 46,X,Y。她们具有良好发育的第二性征,但存在阴道内性交失败。3 名 X、Y 女性成功进行了 EBV。总手术时间为 38-45 分钟。无手术并发症报告,由于牵引方向的改变,也没有报告术后并发症。新阴道的深度分别为 10、11 和 12cm。性交在出院当天开始。双方的插入和满意度评分均增加至 90 分。

结论

与传统球囊阴道成形术相比,将牵引方向居中移动并将导管出口点向上移动是可行且安全的,对于治疗雄激素不敏感综合征导致的盲阴道,其结果明显更好。

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