Department of Craniomaxillofacial Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Science, Peking Union Medical College, No 33, Ba-Da-Chu Road, Shi Jing Shan District, Beijing 100144, China.
J Craniomaxillofac Surg. 2011 Sep;39(6):425-30. doi: 10.1016/j.jcms.2010.10.013. Epub 2010 Nov 4.
The purpose of this study was to research the effect of outer mandibular cortex osteotomy on local morphology and biomechanics in young miniature pigs.
Eight 3-month-old miniature pigs were used as experimental animals to establish an animal model for removing the outer cortex of the mandibular body, and the changes in local morphology, fine structure, and biomechanics of the mandible after the operation were evaluated.
The thickness of the operated side decreased to a greater extent than that of the control side. Further, local histologic structure and biomechanics characteristics could be recovered under stress conditions and were close to those of the normal side after the operation. However, some animals (37.5%) exhibited mandible deviation after operation.
Under normal conditions, mandibular outer cortex osteotomy should not be performed in the case of children.
本研究旨在探讨下颌骨外皮质切开术对幼年小型猪局部形态和生物力学的影响。
8 只 3 月龄小型猪作为实验动物，建立下颌体外侧皮质去除的动物模型，评价术后下颌骨局部形态、超微结构和生物力学的变化。
术侧厚度减小程度大于对照侧。进一步的，在受力条件下，局部组织学结构和生物力学特性可以恢复，与正常侧接近。但部分动物（37.5%）术后出现下颌骨偏斜。
在正常情况下，儿童下颌骨外皮质切开术不应进行。
