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缺血性结肠炎:最终手术的风险因素。

Ischemic colitis: risk factors for eventual surgery.

机构信息

Department of Surgery, Yale University School of Medicine, New Haven, CT 06510, USA.

出版信息

Am J Surg. 2010 Nov;200(5):646-50. doi: 10.1016/j.amjsurg.2010.07.005.

Abstract

BACKGROUND

Ischemic colitis is a common disorder often without clear indications for surgical management. The aim of this study was to identify risk factors that predict the need for surgery.

METHODS

Patients were identified retrospectively based on International Classification of Disease codes and admission over an 8-year period.

RESULTS

A total of 253 patients presented with ischemic colitis. A total of 205 patients were managed nonsurgically, 12 underwent immediate surgery (within 12 hours of presentation), and 36 had delayed surgery. On univariate analysis, risk factors that predicted delayed surgery were peripheral vascular disease, atrial fibrillation, hypotension, tachycardia, absence of bleeding per rectum, free intraperitoneal fluid on computed tomography scan, intensive care unit admission, vasopressors, mechanical ventilation, and increased lactate level on admission. Intraperitoneal fluid on computed tomography scan and absence of bleeding per rectum were predictive of surgical intervention on multivariate analysis.

CONCLUSIONS

In patients with ischemic colitis, several risk factors were associated with the need for subsequent surgery during the same admission. These factors could be used to select patients for immediate surgery before worsening of their clinical condition.

摘要

背景

缺血性结肠炎是一种常见疾病,通常没有明确的手术治疗指征。本研究旨在确定预测手术需求的危险因素。

方法

根据国际疾病分类代码和 8 年期间的入院情况,对患者进行回顾性识别。

结果

共 253 例患者出现缺血性结肠炎。205 例患者接受非手术治疗,12 例患者在就诊后 12 小时内立即手术,36 例患者接受延迟手术。单因素分析显示,预测延迟手术的危险因素包括外周血管疾病、心房颤动、低血压、心动过速、直肠无出血、腹部 CT 扫描有游离腹腔积液、入住重症监护病房、血管加压素、机械通气和入院时乳酸水平升高。腹部 CT 扫描有腹腔积液和直肠无出血是多因素分析中手术干预的预测因素。

结论

在缺血性结肠炎患者中,一些危险因素与同一入院期间后续手术的需求相关。这些因素可用于在患者临床状况恶化之前选择立即手术的患者。

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