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一例罕见的全结肠缺血合并菌血症病例:内科医生对结肠缺血的综述

A Rare Case of Pancolonic Ischemia Complicated by Bacteremia: A Review of Colonic Ischemia for Internists.

作者信息

Chodoff Alaina, Whitehead Diana, Otieno Beryl, Fuscaldo Joseph

机构信息

Department of Internal Medicine, Greater Baltimore Medical Center, Towson, MD, USA.

Department of Gastrointestinal Disease, Director of Inflammatory Bowel Disease, Greater Baltimore Medical Center, Towson, MD, USA.

出版信息

J Community Hosp Intern Med Perspect. 2023 Jun 29;13(4):26-30. doi: 10.55729/2000-9666.1197. eCollection 2023.

DOI:10.55729/2000-9666.1197
PMID:37868229
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10589005/
Abstract

The varied clinical presentation and objective findings associated with colonic ischemia (CI) overlap with multiple disease processes. A high index of suspicion is critical for timely diagnosis and prognostication to avoid delays in treatment. We present a case that highlights the challenges of diagnosing CI and the high morbidity associated with severe disease. Case report: A sixty-four-year-old female presented to our community hospital with acute onset abdominal pain, nausea, and diarrhea, complicated by septic shock. She was initially given a diagnosis of infectious colitis until a colonoscopy was performed revealing extensive pancolonic ulcerations. Histopathological features on biopsy were most consistent with colonic ischemia. Blood cultures grew . Surgery was avoided due to the high morbidity and mortality of performing a total colectomy and ileostomy. The patient continued to struggle with abdominal pain, diarrhea, and hematochezia, consistent with continuous CI, leading to recurrent hospitalizations.

摘要

与结肠缺血(CI)相关的多样临床表现和客观检查结果与多种疾病过程存在重叠。高度的怀疑指数对于及时诊断和预后评估至关重要,以避免治疗延误。我们报告一例病例,该病例突出了诊断CI的挑战以及严重疾病相关的高发病率。病例报告:一名64岁女性因急性腹痛、恶心和腹泻就诊于我们的社区医院,并并发感染性休克。她最初被诊断为感染性结肠炎,直到进行结肠镜检查发现广泛的全结肠溃疡。活检的组织病理学特征最符合结肠缺血。血培养结果为……由于行全结肠切除术和回肠造口术的高发病率和死亡率,避免了手术治疗。患者持续遭受腹痛、腹泻和便血困扰,与持续性结肠缺血相符,导致反复住院。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43ac/10589005/ae5fa120fc58/jchim-13-04-026f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43ac/10589005/ae5fa120fc58/jchim-13-04-026f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43ac/10589005/ae5fa120fc58/jchim-13-04-026f1.jpg

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本文引用的文献

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Ischemic bowel disease in 2021.2021 年的缺血性肠病。
World J Gastroenterol. 2021 Aug 7;27(29):4746-4762. doi: 10.3748/wjg.v27.i29.4746.
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Large Bowel Ischemia/Infarction: How to Recognize It and Make Differential Diagnosis? A Review.大肠缺血/梗死:如何识别及进行鉴别诊断?综述
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Colon ischemia: A comprehensive review.结肠缺血:全面综述。
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Ischaemic colitis.缺血性结肠炎
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ACG clinical guideline: epidemiology, risk factors, patterns of presentation, diagnosis, and management of colon ischemia (CI).美国胃肠病学会临床指南:结肠缺血(CI)的流行病学、危险因素、临床表现模式、诊断及管理
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A population-based study of incidence, risk factors, clinical spectrum, and outcomes of ischemic colitis.一项基于人群的缺血性结肠炎发病率、危险因素、临床谱及预后的研究。
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Colorectal Dis. 2012 Nov;14(11):e751-63. doi: 10.1111/j.1463-1318.2012.03171.x.