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[粘连与慢性盆腔疼痛]

[Adhesions and chronic pelvic pain].

作者信息

Roman H, Bourdel N, Canis M, Rigaud J, Delavierre D, Labat J-J, Sibert L

机构信息

Clinique gynécologique et obstétricale, CHU de Rouen, 76000 Rouen, France.

出版信息

Prog Urol. 2010 Nov;20(12):1003-9. doi: 10.1016/j.purol.2010.08.003. Epub 2010 Sep 29.

DOI:10.1016/j.purol.2010.08.003
PMID:21056378
Abstract

OBJECTIVES

To analyse pathophysiology of adhesions and their link with chronic pelvic pain, as well as therapeutic and prevention options as reported in the literature.

MATERIAL AND METHODS

Review of articles and consensus conferences published on this topic in the Medline (Pubmed) database, selected according to their scientific relevance.

RESULTS

Postoperative adhesions are responsible for a specific morbidity combining chronic pain, small bowel obstruction, infertility, and morbidity increase in the event of subsequent surgery. Chronic pains in previously operated on patients can be linked to postoperative adhesions. Ultrasonography and dynamic MRI can recognize intra abdominal adhesions, but cannot definitely link them to the painful symptoms. The prevention of adhesions is done firstly by respecting surgical rules concerning laparoscopic and open surgical approaches, and secondly by the use of anti-adhesion products. Pharmacological adhesion prevention systems decrease the frequency and extent of adhesions. Their efficiency has been proved by studies with substantial evidence levels. Patients suffering from potentially adhesion-induced chronic abdominal and pelvic pains can benefit from a laparoscopic adhesiolysis, which improved pain symptoms in more than 50% of patients, but exposes to the risk of complications, such as bowel injury.

CONCLUSION

The decision to perform adhesiolysis should be taken for each patient individually, while taking in consideration the benefit-to-risk ratio. Adhesion relapse after adhesiolysis is a frequent phenomenon, but can be reduced by the use of anti-adhesion products.

摘要

目的

分析粘连的病理生理学及其与慢性盆腔痛的联系,以及文献报道的治疗和预防方法。

材料与方法

回顾Medline(Pubmed)数据库中发表的关于该主题的文章和共识会议,根据其科学相关性进行筛选。

结果

术后粘连会导致特定的发病率,包括慢性疼痛、小肠梗阻、不孕,以及后续手术时发病率增加。既往接受过手术的患者出现的慢性疼痛可能与术后粘连有关。超声检查和动态磁共振成像可识别腹腔内粘连,但无法明确将其与疼痛症状联系起来。粘连的预防首先要遵守腹腔镜和开放手术入路的手术规则,其次是使用抗粘连产品。药物性粘连预防系统可降低粘连的频率和程度。大量证据水平的研究已证实其有效性。患有可能由粘连引起的慢性腹部和盆腔疼痛的患者可受益于腹腔镜粘连松解术,该手术可使超过50%的患者疼痛症状得到改善,但存在肠损伤等并发症风险。

结论

粘连松解术的决策应针对每个患者单独做出,同时考虑利弊比。粘连松解术后粘连复发是常见现象,但使用抗粘连产品可降低复发率。

相似文献

1
[Adhesions and chronic pelvic pain].[粘连与慢性盆腔疼痛]
Prog Urol. 2010 Nov;20(12):1003-9. doi: 10.1016/j.purol.2010.08.003. Epub 2010 Sep 29.
2
Adhesions in patients with chronic pelvic pain: a role for adhesiolysis?慢性盆腔疼痛患者的粘连:粘连松解术能发挥作用吗?
Fertil Steril. 2004 Dec;82(6):1483-91. doi: 10.1016/j.fertnstert.2004.07.948.
3
Adhesion controversies: pelvic pain as a cause of adhesions, crystalloids in preventing them.粘连争议:盆腔疼痛作为粘连的一个原因,晶体在预防粘连方面的作用。
J Reprod Med. 1996 Jan;41(1):19-26.
4
Adolescent chronic pelvic pain.青少年慢性盆腔疼痛。
J Pediatr Adolesc Gynecol. 2005 Dec;18(6):371-7. doi: 10.1016/j.jpag.2005.09.001.
5
Diagnosis and treatment of chronic pelvic pain.
Practitioner. 1998 Feb;242(1583):120-3, 125.
6
Disorders of adhesions or adhesion-related disorder: monolithic entities or part of something bigger--CAPPS?粘连性疾病或与粘连相关的疾病:单一实体还是更大范畴的一部分——CAPPS?
Semin Reprod Med. 2008 Jul;26(4):356-68. doi: 10.1055/s-0028-1082394.
7
Chronic pelvic pain in women.女性慢性盆腔疼痛
Postgrad Med J. 2009 Jan;85(999):24-9. doi: 10.1136/pgmj.2008.073494.
8
Relationship of pelvic infection and chronic pelvic pain.盆腔感染与慢性盆腔疼痛的关系。
Obstet Gynecol Clin North Am. 1993 Dec;20(4):699-708.
9
[Retrospective study of pelviscopic adhesiolysis for treatment of chronic lower abdominal pain (January 1996-December 1997)].
Zentralbl Gynakol. 2000;122(7):368-73.
10
[The place of pelvic adhesions in gynecology. Possibilities of prevention].[盆腔粘连在妇科中的地位。预防的可能性]
Orv Hetil. 1997 Oct 5;138(40):2511-6.

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