Bakalara N, Collet J, Planells R, Thouveny Y, Fontes M
Laboratoire de Biologie de la Differenciation Cellulaire, Faculté de Luminy, Marseille, France.
Biochem Biophys Res Commun. 1990 Jan 15;166(1):66-73. doi: 10.1016/0006-291x(90)91912-c.
In Drosophila melanogaster (Dm), polypeptidic domains have been found in different morphogenetic genes. Two types of them are characterized by the repetition of nucleotidic triplets: the M repeat (CAX) and the paired repeat (CAXCCX). In this paper we described a third type of repeat isolated from the genome of a Polychaete annelid: Owenia fusiformis. This repeat is characterized by the repetition of the triplet CCPurine. Phylogenetic studies showed the presence of this repeat in all the invertebrate genomes tested (eight copies in Dm genome) while we failed to detect it in vertebrate genomes.
在黑腹果蝇(Dm)中,已在不同的形态发生基因中发现了多肽结构域。其中两种类型的特征是核苷酸三联体的重复:M重复序列(CAX)和配对重复序列(CAXCCX)。在本文中,我们描述了从多毛纲环节动物纺锤欧文蚓的基因组中分离出的第三种重复序列类型。这种重复序列的特征是三联体CC嘌呤的重复。系统发育研究表明,在所有测试的无脊椎动物基因组中都存在这种重复序列(Dm基因组中有八个拷贝),而我们在脊椎动物基因组中未能检测到它。