小冠状动脉血管成形术：结果与技术考量
Small coronary vessel angioplasty: outcomes and technical considerations.
作者信息
Rathore Sudhir
机构信息
Department of Cardiology, St George's Healthcare NHS Trust, London, UK.
出版信息
Vasc Health Risk Manag. 2010 Oct 21;6:915-22. doi: 10.2147/VHRM.S8161.
Abstract
Small vessel (<3 mm) coronary artery disease is common and has been identified as independent predictor of restenosis after percutaneous coronary intervention. It remains controversial whether bare-metal stent (BMS) implantation in small vessels has an advantage over balloon angioplasty in terms of angiographic and clinical outcomes. Introduction of drug-eluting stent (DES) has resulted in significant reduction in restenosis and the need for repeat revascularization. Several DESs have been introduced resulting in varying reduction in outcomes as compared with BMS. However, their impact on outcomes in small vessels is not clearly known. It is expected that DES could substantially reduce restenosis in smaller vessels. Large, randomized studies are warranted to assess the impact of different DESs on outcomes in patients with small coronary arteries.
摘要
小血管（<3毫米）冠状动脉疾病很常见，并且已被确定为经皮冠状动脉介入治疗后再狭窄的独立预测因素。就血管造影和临床结果而言，在小血管中植入裸金属支架（BMS）是否比球囊血管成形术更具优势仍存在争议。药物洗脱支架（DES）的引入已使再狭窄和重复血管重建的需求显著减少。几种DES已被引入，与BMS相比，其在降低结果方面存在差异。然而，它们对小血管结果的影响尚不清楚。预计DES可大幅降低较小血管中的再狭窄。有必要进行大型随机研究，以评估不同DES对小冠状动脉患者结果的影响。
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