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舒尼替尼治疗晚期肾细胞癌引起的双侧视乳头水肿。

Bilateral papilledema on sunitinib therapy for advanced renal cell carcinoma.

机构信息

Ballarat Base Hospital, Drummond Street North, Ballarat, VIC 3350, Australia.

出版信息

Med Oncol. 2011 Dec;28 Suppl 1:S395-7. doi: 10.1007/s12032-010-9719-5. Epub 2010 Nov 4.

DOI:10.1007/s12032-010-9719-5
PMID:21057897
Abstract

We report the case of a 59-year-old man with advanced renal cell carcinoma who developed bilateral papilledema while on therapy with sunitinib, a multi-targeted tyrosine kinase inhibitor (TKI). While papilledema has been reported in association with another TKI (imatinib), the association between sunitinib and papilledema has not previously been reported in the literature.

摘要

我们报告了一例 59 岁男性病例,他在接受舒尼替尼(一种多靶点酪氨酸激酶抑制剂[TKI])治疗期间出现双侧视乳头水肿。虽然已有报道称另一种 TKI(伊马替尼)与视乳头水肿有关,但舒尼替尼与视乳头水肿之间的关联以前尚未在文献中报道过。

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Probable ponatinib-induced papilledema in a patient with acute lymphocytic leukemia.一名急性淋巴细胞白血病患者可能由波纳替尼引起的视乳头水肿。

本文引用的文献

1
Reversible posterior leucoencephalopathy syndrome associated with sunitinib.
Intern Med J. 2009 May;39(5):341-2. doi: 10.1111/j.1445-5994.2009.01908.x. Epub 2009 Apr 20.
2
Tolerability of first-line therapy for metastatic renal cell carcinoma.转移性肾细胞癌一线治疗的耐受性
Cancer Treat Rev. 2009 May;35(3):297-307. doi: 10.1016/j.ctrv.2008.12.003. Epub 2009 Feb 26.
3
Targeted therapies for metastatic renal cell carcinoma: an overview of toxicity and dosing strategies.转移性肾细胞癌的靶向治疗:毒性及给药策略概述
Am J Ophthalmol Case Rep. 2023 Oct 6;32:101933. doi: 10.1016/j.ajoc.2023.101933. eCollection 2023 Dec.
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4
Optic disc edema as a possible complication of Imatinib mesylate (Gleevec).视盘水肿作为甲磺酸伊马替尼(格列卫)的一种可能并发症。
Jpn J Ophthalmol. 2008 Jul-Aug;52(4):331-333. doi: 10.1007/s10384-008-0561-7. Epub 2008 Sep 5.
5
Clinical spectrum of reversible posterior leukoencephalopathy syndrome.可逆性后部白质脑病综合征的临床谱
Arch Neurol. 2008 Feb;65(2):205-10. doi: 10.1001/archneurol.2007.46.
6
Ocular side effects in chronic myeloid leukemia patients treated with imatinib.
Leuk Res. 2008 Jul;32(7):1022-5. doi: 10.1016/j.leukres.2007.10.016. Epub 2007 Dec 3.
7
Sunitinib induced hypertension, thrombotic microangiopathy and reversible posterior leukencephalopathy syndrome.舒尼替尼诱发高血压、血栓性微血管病及可逆性后部白质脑病综合征。
Ann Oncol. 2007 Oct;18(10):1745-7. doi: 10.1093/annonc/mdm454.
8
Treatment options in renal cell carcinoma: past, present and future.肾细胞癌的治疗选择:过去、现在与未来
Ann Oncol. 2007 Sep;18 Suppl 10:x25-31. doi: 10.1093/annonc/mdm411.
9
Reversible posterior leukoencephalopathy syndrome induced by sunitinib.舒尼替尼诱发的可逆性后部白质脑病综合征
J Clin Oncol. 2007 Aug 10;25(23):3559. doi: 10.1200/JCO.2007.12.8710.
10
BCR-ABL tyrosine kinase inhibitors for chronic myelogenous leukemia.用于慢性粒细胞白血病的BCR-ABL酪氨酸激酶抑制剂
N Engl J Med. 2007 Jul 19;357(3):258-65. doi: 10.1056/NEJMct071828.