Division of Neurology, University of Toronto, Toronto, Ontario, Canada.
Can J Neurol Sci. 2010 Sep;37(5):656-61. doi: 10.1017/s0317167100010854.
To determine the correlation between frontal intermittent rhythmic delta activity (FIRDA) and the clinical and radiological correlates in children.
Retrospective review of the EEG and imaging studies of 37 children with documented FIRDA.
FIRDA was associated with multiple neurological conditions and not necessarily with midline lesions. Patients with abnormal neurological exam had a longer FIRDA duration (average 9.5 seconds) compared to children with no reported abnormal examination (average of 6.5 seconds). FIRDA ranged from 2 to 2.5 Hz (n = 15), 3 Hz (n = 17) and from 1.5 to 3 Hz (n = 5) and there was a significant association between the duration of FIRDA and abnormal laboratory tests (p. < 0.05, Student's T test).
FIRDA was not correlated with midline brain lesions in children. FIRDA may be a non specific oscillation of an unhealthy pediatric brain with or without seizures.
确定儿童额部间歇性节律性 delta 活动（FIRDA）与临床和影像学相关性之间的关系。
对 37 例经证实存在 FIRDA 的儿童的脑电图和影像学研究进行回顾性分析。
FIRDA 与多种神经疾病相关，而不一定与中线病变相关。与无报告异常检查的儿童（平均 6.5 秒）相比，神经检查异常的患者 FIRDA 持续时间更长（平均 9.5 秒）。FIRDA 的频率范围为 2 至 2.5 Hz（n = 15）、3 Hz（n = 17）和 1.5 至 3 Hz（n = 5），且 FIRDA 的持续时间与异常实验室检查之间存在显著相关性（p < 0.05，Student's T 检验）。
FIRDA 与儿童中线脑病变无关。FIRDA 可能是一种无癫痫或伴有癫痫的不健康儿童大脑的非特异性振荡。
