Horrevorts A M, Borst J, Puyk R J, De Ridder R, Dzoljicdanilovic G, Degener J E, Kerrebijn K F, Michel M F
Department of Clinical Microbiology, Erasmus University, Rotterdam, The Netherlands.
J Med Microbiol. 1990 Feb;31(2):119-24. doi: 10.1099/00222615-31-2-119.
The occurrence of various Pseudomonas aeruginosa strains in the sputum of 15 patients with cystic fibrosis (CF) was monitored over periods ranging from 2 to 60 months. Isolates of P. aeruginosa were typed by four different techniques, namely serotyping, active and passive pyocin typing, and phage typing. The maximum number of different serotypes found in the patients was three (one serotype in nine patients; two serotypes in five patients; three serotypes in one patient). Pyocin and phage typing showed no marked differences between strains of the same serotype in individual patients. Exacerbations of chronic respiratory infection were not associated with changes in the sputum flora, the composition of P. aeruginosa strains in which remains constant over long periods in patients with CF.
对15名囊性纤维化（CF）患者痰液中不同铜绿假单胞菌菌株进行了为期2至60个月的监测。采用四种不同技术对铜绿假单胞菌分离株进行分型，即血清分型、主动和被动绿脓菌素分型以及噬菌体分型。患者中发现的不同血清型的最大数量为三种（9名患者为一种血清型；5名患者为两种血清型；1名患者为三种血清型）。绿脓菌素和噬菌体分型显示，个体患者中相同血清型的菌株之间无明显差异。慢性呼吸道感染的加重与痰液菌群的变化无关，CF患者痰液中铜绿假单胞菌菌株的组成在很长一段时间内保持不变。
