Agrawal P, Laloraya M M
Acta Anat (Basel). 1978;102(3):276-93. doi: 10.1159/000145648.
A comparative study of the enzymes delta5-3beta-HSD, cytochrome oxidase and peroxidase has been made in the ovaries and uterus of mammals (mouse, guinea pig, cat and dog) during various reproductive phases. The granulosa cells of developing follicles, hypertrophied interstitial cells of thecal origin and the luteal cells show intense delta5-3beta-HSD and cytochrome oxidase activity. Peroxidases are found to be present in the corpus luteum and the epithelial cords of thecal origin. delta5-3beta-HSD and cytochrome oxidase activity is localized to the endometrium and myometrium of mature and pregnant uterus of mouse and guinea pig, while peroxidase is seen only in the decidua and endometrial glands of pregnant animals. The significance of these enzymes is discussed in relation to the cellular basis of luteinization and steroid hormone synthesis.
在哺乳动物（小鼠、豚鼠、猫和狗）的不同生殖阶段，对卵巢和子宫中的δ5-3β-羟类固醇脱氢酶、细胞色素氧化酶和过氧化物酶进行了比较研究。发育卵泡的颗粒细胞、卵泡膜来源的肥大间质细胞和黄体细胞显示出强烈的δ5-3β-羟类固醇脱氢酶和细胞色素氧化酶活性。发现过氧化物酶存在于黄体和卵泡膜来源的上皮索中。δ5-3β-羟类固醇脱氢酶和细胞色素氧化酶活性定位于小鼠和豚鼠成熟及妊娠子宫的子宫内膜和子宫肌层，而过氧化物酶仅见于妊娠动物的蜕膜和子宫内膜腺。结合黄体化和类固醇激素合成的细胞基础，讨论了这些酶的意义。
