Mengden T, Marincek B, Zynamon A, Vetter W
Departement für Innere Medizin, Universitätsspital Zürich.
Schweiz Rundsch Med Prax. 1990 Jan 23;79(4):74-8.
A 42-year-old man with multiple cutaneous neurofibromacules, café-au-lait and gangrene of toes was diagnosed having neurofibromatosis in 1976. An aortography performed because of severe hypertension had shown a coarctation and bilateral renal artery stenosis in 1982. Conservative antihypertensive therapy with an ACE-inhibitor, a vasodilatating agent and a diuretic resulted in gradual normalisation of blood pressure values. A recent follow-up revealed minimal progression of neurofibromatosis and hypertensive lesions documenting a benign course for over 13 years.
一名42岁男性,有多处皮肤神经纤维瘤、咖啡斑和脚趾坏疽,于1976年被诊断为神经纤维瘤病。1982年因严重高血压进行的主动脉造影显示有主动脉缩窄和双侧肾动脉狭窄。使用血管紧张素转换酶抑制剂、血管扩张剂和利尿剂进行的保守抗高血压治疗使血压值逐渐恢复正常。最近的一次随访显示神经纤维瘤病和高血压性病变进展甚微,证明病程良性超过13年。