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[重型颅脑损伤后不同意识障碍患者脑生物电活动时空组织紊乱的特点]

[Peculiarities of disorders of brain bioelectrical activity spatial-time organization in patients with different consciousness depression after severe head injury].

作者信息

Klimash A V, Tsitseroshin M N, Shepoval'nikov A N, Zaĭtseva L G, Kondakov E N, Borovikova V N

出版信息

Fiziol Cheloveka. 2010 Sep-Oct;36(5):49-65.

PMID:21061670
Abstract

Specific changes of bioelectrical brain activity was found in 27 patients with different level of posttraumatic consciousness depression by the methods of crosscorrelation, coherence and factor analysis of EEG. The changes of activity of morphofunctional systems of intracerebral integrations were revealed partially by decreasing of unspecific activity from brainstem structures reflected with increasing of slow wave activity and decreasing of EEG coherence in alpha- and beta-range. Depression of system organization of interconnections of bioelectrical brain activity in frontal and occipital regions of both hemispheres was also detected, and testified about decreasing of intercortical and thalamocortical brain system action under brain dislocation. The changes of integrative brain system activity, provides interhemispheric interaction, had the specific characted. Our results propose a "facilitation" of activity of system, providing "direct" interhemispheric connections through corpus callosum and other commissural tracts of telencephalon as a sequel of mesodiencephalon structures depression with steady reciprocal, antiphase relations of slow weve activity in symmetrical areas of hemispheres in coma II patients. The data of our research had shown no complete disintegration of system brain activity in coma II patients in spite of consciousness and brainstem reflexes depression.

摘要

通过脑电图的互相关、相干性和因子分析方法,在27例不同程度创伤后意识障碍的患者中发现了脑生物电活动的特定变化。脑内整合的形态功能系统活动的变化部分表现为脑干结构非特异性活动的降低,这反映为慢波活动增加以及α和β频段脑电图相干性降低。还检测到双侧大脑半球额叶和枕叶区域脑生物电活动相互连接的系统组织抑制,这证明了脑移位时皮质间和丘脑皮质脑系统作用的降低。提供半球间相互作用的整合脑系统活动变化具有特定特征。我们的结果表明,作为中脑间脑结构抑制的结果,通过胼胝体和端脑其他连合束提供“直接”半球间连接的系统活动“促进”,在Ⅱ型昏迷患者半球对称区域慢波活动具有稳定的相互、反相关系。我们的研究数据表明,尽管Ⅱ型昏迷患者存在意识和脑干反射抑制,但脑系统活动并未完全瓦解。

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[Peculiarities of disorders of brain bioelectrical activity spatial-time organization in patients with different consciousness depression after severe head injury].[重型颅脑损伤后不同意识障碍患者脑生物电活动时空组织紊乱的特点]
Fiziol Cheloveka. 2010 Sep-Oct;36(5):49-65.
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Different neuronal networks are associated with spikes and slow activity in hypsarrhythmia.不同的神经网络与高峰节律紊乱中的尖峰和慢波活动相关。
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[The characteristics of the bioelectrical activity of the human brain in lesions of different sections of the corpus callosum].
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[Intercentral correlations in the cerebral cortex according to the EEG coherence index after restoration of consciousness and speech following prolonged coma].[长时间昏迷后意识和言语恢复后脑电图相干指数所反映的大脑皮质中枢间相关性]
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