Sousa Tatiana S, Matherne Ryan J, Wilkerson Michael G
University of Texas Medical Branch, Department of Internal Medicine, Galveston, TX 77555-0783, USA.
J Drugs Dermatol. 2010 Nov;9(11):1439-42.
Nontuberculous mycobacterial (NTM) infections are on the rise and often cause skin diseases that are misdiagnosed. The authors present three cases of atypical mycobacterial infections in insulin-dependent diabetics occurring in sites of subcutaneous insulin injections. One of the patients was vitamin D deficient at the time of infection with NTM. The history and clinical presentation of the cases are presented; pathogenesis and treatment are discussed in conjunction with the correlation of mycobacterial disease susceptibility with vitamin D deficiency.
非结核分枝杆菌(NTM)感染呈上升趋势,且常引发被误诊的皮肤病。作者报告了3例胰岛素依赖型糖尿病患者在皮下胰岛素注射部位发生非典型分枝杆菌感染的病例。其中1例患者在感染NTM时存在维生素D缺乏。本文介绍了这些病例的病史和临床表现,并结合分枝杆菌病易感性与维生素D缺乏的相关性讨论了发病机制和治疗方法。