Kitis Ali, Altug Filiz, Cavlak Ugur, Akdag Beyza
School of Physical Therapy and Rehabilitation, Pamukkale University, Denizli, Turkey. Tel/Fax. +90 (258) 2655487. E-mail:
Neurosciences (Riyadh). 2008 Jan;13(1):29-36.
To investigate the relationship between physical functioning, non-physical functioning, and upper extremity functional abilities in patients with multiple sclerosis (MS) and healthy subjects.
A total of 63 patients with MS [Expanded Disability Status Scale (EDSS) score; 3-8] and 52 healthy subjects attending the Pamukkale University, School of Physical Therapy and Rehabilitation in Denizli, Turkey were studied in the period from February 2006 to June 2006. To allow further evaluation, 63 individuals with MS were divided into 2 groups according to their ambulation ability level. The physical functioning was assessed with the Functional Independence Measure (FIM), the Purdue Pegboard Test, and the Jebsen Hand Function Test, and the non-physical functioning was assessed with the Beck Depression Inventory (BDI).
Depressive symptoms were significantly elevated in the MS group versus the control group based on the BDI (p<0.0001). In MS subjects, while there was good positive correlation between EDSS and BDI scores, there was a good negative correlation between EDSS and FIM scores (p<0.0001).
Non-physical functioning, especially depression, is strongly associated with activities of daily living and decreases functional abilities in MS patients. For this reason, we recommend that non-physical functioning should also be evaluated in patients with MS to plan the most suitable physical therapy program.
探讨多发性硬化症(MS)患者与健康受试者的身体功能、非身体功能及上肢功能能力之间的关系。
2006年2月至2006年6月,对土耳其代尼兹利棉花堡大学物理治疗与康复学院的63例MS患者[扩展残疾状态量表(EDSS)评分;3 - 8分]和52例健康受试者进行了研究。为了进行进一步评估,将63例MS患者根据其行走能力水平分为2组。采用功能独立性测量(FIM)、普渡钉板试验和杰布森手功能试验评估身体功能,采用贝克抑郁量表(BDI)评估非身体功能。
基于BDI,MS组的抑郁症状较对照组显著升高(p<0.0001)。在MS受试者中,EDSS与BDI评分之间呈良好的正相关,而EDSS与FIM评分之间呈良好的负相关(p<0.0001)。
非身体功能,尤其是抑郁,与MS患者的日常生活活动密切相关,并降低其功能能力。因此,我们建议对MS患者也应评估非身体功能,以制定最合适的物理治疗方案。