[N-azidomethylbenzoyl blocking group in the phosphotriester synthesis of oligonucleotides].
作者信息
Efimov V A, Aralov A V, Grachev S A, Chakhmakhcheva O G
出版信息
Bioorg Khim. 2010 Sep-Oct;36(5):681-7. doi: 10.1134/s1068162010050110.
PMID:21063455
Abstract
An effective modification of phosphotriester method for automatic synthesis of DNA and RNA fragments using O-nucleophilic intramolecular catalysis and 2-(azidometil)benzoyl group to protect amino groups of heterocyclic bases of nucleotides is described.
摘要
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