Goren M P, Pratt C B
Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee 38101.
Cancer Chemother Pharmacol. 1990;25(5):371-2. doi: 10.1007/BF00686240.
The sulfhydryl mesna is increasingly used to protect the bladder and kidney from effects of chemotherapy with ifosfamide and cyclophosphamide. Mesna reacts with reagents on urinary test strips designed to detect ketones. Test-strip results were correlated to sulfhydryl concentrations in 931 urine specimens obtained after infusions of mesna. These data may be used to estimate urinary mesna concentrations at the bedside or to test compliance in outpatients given oral mesna therapy.
巯基乙磺酸钠越来越多地用于保护膀胱和肾脏免受异环磷酰胺和环磷酰胺化疗的影响。巯基乙磺酸钠与尿试纸条上用于检测酮类的试剂发生反应。在输注巯基乙磺酸钠后获得的931份尿液标本中，将试纸条检测结果与巯基浓度进行了关联分析。这些数据可用于在床边估计尿液中巯基乙磺酸钠的浓度，或用于检测接受口服巯基乙磺酸钠治疗的门诊患者的依从性。
