Multiple myeloma and pregnancy.

Pregnancy has been reported in patients with hematological malignancies, such as acute leukemia, Hodgkin and malignant lymphoma and chronic myelocytic leukemia. Only 12 cases of pregnancy occurring in patients with multiple myeloma (MM) have been reported. The present report describes 6 additional cases of this rare association that received chemotherapy during pregnancy, including in the first trimester. The newborns were 3 male and 3 female with weight >2500 g and without evidence of fetal malformations. Longer follow-up (>3 years) did not give evidence of late complications in the children. Three mothers received stem cell transplantation.