Roberts H J
Good Samaritan Hospital, West Palm Beach.
J Fla Med Assoc. 1990 Feb;77(2):86-90.
Aplastic anemia, pure red cell aplasia, leukemia, lymphoma and other hematologic disorders have followed exposure to products containing the pesticide pentachlorophenol (PCP). Information in a 25-year compilation of documented case reports is summarized, involving industrial and home exposure and accidental poisoning in a nursery. The potential hematologic, mutagenic and carcinogenic effects of PCP and its dioxin-dibenzofuran contaminants also are reviewed. Owing to widespread contamination of the environment by PCP products, and latent periods of up to several decades after exposure before these disorders become manifest clinically, it is necessary to consider their etiologic or contributory role. These issues continue to surface in toxic tort litigation relative to causation.
再生障碍性贫血、纯红细胞再生障碍、白血病、淋巴瘤及其他血液系统疾病都与接触含农药五氯苯酚（PCP）的产品有关。本文总结了一份25年的文献病例报告汇编中的信息，这些病例涉及工业接触、家庭接触以及托儿所的意外中毒。同时还综述了五氯苯酚及其二恶英 - 二苯并呋喃污染物潜在的血液学、致突变和致癌作用。由于五氯苯酚产品对环境的广泛污染，以及接触后长达数十年的潜伏期这些疾病才会在临床上显现，因此有必要考虑它们在病因学上的作用或促成作用。在与因果关系相关的有毒侵权诉讼中，这些问题仍不断出现。
