Kitano K, Konoeda C, Tanaka M
Department of Cardiothoracic Surgery, The University of Tokyo, Graduate School of Medicine, Tokyo, Japan.
Kyobu Geka. 2010 Nov;63(12):1045-8.
A case of undifferentiated pleomorphic sarcoma in the mediastinum is presented. A 74-year-old man with no complaint was referred to our department for treatment of mediastinal mass pointed out by chest X-ray. Chest computed tomography (CT) revealed 3 tumors located in the left mediastinum. The largest one was adjacent to the esophagus with 10 cm in diameter. The other one was located beneath the left inferior pulmonary vein, and the last adjacent to the pulmonary artery trunk. Complete extirpation of the tumors was unsuccessful because of the invasion to the pulmonary artery trunk. A diagnosis of undifferentiated pleomorphic sarcoma was made with negative immunohistochemical staining for markers except for vimentin. Tumor cells were found to be scattered in the partially resected thymus. We assume this is a rare presentation of mediastinal dissemination of the tumor.
本文报告一例纵隔未分化多形性肉瘤。一名74岁男性,无任何不适,因胸部X线检查发现纵隔肿块而转诊至我科。胸部计算机断层扫描(CT)显示左纵隔有3个肿瘤。最大的一个与食管相邻,直径10厘米。另一个位于左下肺静脉下方,最后一个与肺动脉主干相邻。由于肿瘤侵犯肺动脉主干,未能成功完整切除肿瘤。除波形蛋白外,免疫组化染色标记物均为阴性,诊断为未分化多形性肉瘤。在部分切除的胸腺中发现肿瘤细胞散在分布。我们认为这是肿瘤纵隔播散的一种罕见表现。