Kosaka Makoto, Chiaki Tomoshige, Yokoyama Toshiki, Koizumi Tomonori, Shinohara Naohiro, Kubo Keishi
First Department of Internal Medicine, Shinshu University School of Medicine.
Nihon Kokyuki Gakkai Zasshi. 2010 Oct;48(10):729-33.
An 80-year-old man was admitted to our hospital with a 4.0 x 2.0 cm shadow accompanied by calcification, found on chest CT scans on a health check. The shadow was located in the left lower lobe (S10), and was attached to the pleura. A transbronchial biopsy did not yield a definitive diagnosis. A percutaneous needle biopsy yielded a diagnosis of leiomyosarcoma. A general examination did not show any metastatic lesions in other areas. However, the tumor grew rapidly, with pleural effusion, and therefore he was treated only by palliative therapy. He died from respiratory failure 90 days after onset. The primary site of the tumor was determined to be intrapulmonary area by radiographic and autopsy findings. We report a rare primary pulmonary leiomyosarcoma showing rapid growth and fatal outcome.
一名80岁男性因健康检查时胸部CT扫描发现一个伴有钙化的4.0×2.0厘米阴影而入住我院。该阴影位于左下叶（S10），与胸膜相连。经支气管活检未能得出明确诊断。经皮针吸活检确诊为平滑肌肉瘤。全身检查未发现其他部位有转移病灶。然而，肿瘤生长迅速并伴有胸腔积液，因此仅对其进行了姑息治疗。发病90天后，他死于呼吸衰竭。根据影像学和尸检结果，肿瘤的原发部位确定为肺内区域。我们报告了一例罕见的原发性肺平滑肌肉瘤，其生长迅速且预后不良。
