Arif Muhammad, Iqbal Zafar
Department of Ophthalmology, Khyber Teaching Hospital, Peshawar, Pakistan.
J Ayub Med Coll Abbottabad. 2009 Oct-Dec;21(4):60-2.
Retinoblastoma is a malignant intraocular tumour of childhood, if not detected early, it results in loss of eye as well as life. The Objective was to study the pattern of presentation of Retinoblastoma in order to detect the disease at an earlier stage. It was conducted at Supra Regional Referral Centre for Retinoblastoma, Department of Ophthalmology, Khyber Teaching Hospital, Peshawar, Pakistan from 1st July 1999 to 30th September 2002.
Seventy patients were registered and admitted for diagnostic evaluation. After initial interview a proforma was filled about history of disease. Examination under anaesthesia included indirect ophthalmoscopy with indentation. B-scan of the eye and CT scan of the Orbit was done when required.
Forty (57.14%) patients presented with Leukocoria; other presentation included hyphaema, strabismus, proptosis, 56.48% patients presented in stage VB (Rees Elsworth classification).
Early detection through better understanding of presenting features of the disease and application of diagnostic skills can reduce the advanced stage of Retinoblastoma.
视网膜母细胞瘤是一种儿童期的恶性眼内肿瘤,若不及早发现,会导致失明甚至死亡。目的是研究视网膜母细胞瘤的临床表现模式,以便在更早阶段发现该疾病。该研究于1999年7月1日至2002年9月30日在巴基斯坦白沙瓦开伯尔教学医院眼科视网膜母细胞瘤超区域转诊中心进行。
70名患者登记入院进行诊断评估。初次问诊后填写一份关于疾病史的表格。麻醉下检查包括间接检眼镜检查及压迫检查。必要时进行眼部B超扫描和眼眶CT扫描。
40名(57.14%)患者表现为白瞳症;其他表现包括前房积血、斜视、眼球突出,56.48%的患者处于VB期(里斯·埃尔斯沃思分类法)。
通过更好地了解疾病的表现特征并应用诊断技术进行早期检测,可以降低视网膜母细胞瘤的晚期发生率。