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三阴性乳腺癌。

Triple-negative breast cancer.

机构信息

Departmentof Oncology and Human Genetics, Research Institute of the McGill University Health Centre, and the Lady Davis Institute of the Jewish General Hospital, McGill University, Montreal, QC H2W 1S6, Canada.

出版信息

N Engl J Med. 2010 Nov 11;363(20):1938-48. doi: 10.1056/NEJMra1001389.

DOI:10.1056/NEJMra1001389
PMID:21067385
Abstract

Triple-negative breast cancer, so called because it lacks expression of the estrogen receptor, progesterone receptor, and HER2, is often, but not always, a basal-like breast cancer. This review focuses on its origin, molecular and clinical characteristics, and treatment.

摘要

三阴性乳腺癌,之所以这样命名是因为它缺乏雌激素受体、孕激素受体和 HER2 的表达,通常是基底样乳腺癌,但也并非总是如此。这篇综述重点介绍了它的起源、分子和临床特征以及治疗。

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Triple-negative breast cancer.三阴性乳腺癌。
N Engl J Med. 2010 Nov 11;363(20):1938-48. doi: 10.1056/NEJMra1001389.
2
Triple-negative breast cancer: current state of the art.三阴性乳腺癌:当前的技术水平
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What is triple-negative breast cancer?什么是三阴性乳腺癌?
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The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes.三阴性悖论:乳腺癌亚型的原发性肿瘤化疗敏感性
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The triple-negative subtype: new ideas for the poorest prognosis breast cancer.三阴性亚型:针对预后最差的乳腺癌的新见解。
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"Targeting" triple-negative breast cancer: the lessons learned from BRCA1-associated breast cancers.针对三阴性乳腺癌:BRCA1 相关乳腺癌的经验教训。
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Basal cytokeratin and epidermal growth factor receptor expression are not predictive of BRCA1 mutation status in women with triple-negative breast cancers.基底细胞角蛋白和表皮生长因子受体的表达与三阴性乳腺癌女性的 BRCA1 突变状态无关。
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Therapeutic options for triple-negative breast cancers with defective homologous recombination.同源重组缺陷的三阴性乳腺癌的治疗选择
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