三阴性乳腺癌。

Triple-negative breast cancer.

机构信息

Departmentof Oncology and Human Genetics, Research Institute of the McGill University Health Centre, and the Lady Davis Institute of the Jewish General Hospital, McGill University, Montreal, QC H2W 1S6, Canada.

出版信息

N Engl J Med. 2010 Nov 11;363(20):1938-48. doi: 10.1056/NEJMra1001389.

DOI:10.1056/NEJMra1001389

PMID:21067385

Abstract

Triple-negative breast cancer, so called because it lacks expression of the estrogen receptor, progesterone receptor, and HER2, is often, but not always, a basal-like breast cancer. This review focuses on its origin, molecular and clinical characteristics, and treatment.

摘要

三阴性乳腺癌，之所以这样命名是因为它缺乏雌激素受体、孕激素受体和 HER2 的表达，通常是基底样乳腺癌，但也并非总是如此。这篇综述重点介绍了它的起源、分子和临床特征以及治疗。