Ceramic Physics Laboratory & Research Institute for Nanoscience, Kyoto Institute of Technology, Sakyo-ku, Matsugasaki, Kyoto, Japan.
J Biomater Sci Polym Ed. 2011;22(16):2165-84. doi: 10.1163/092050610X537129. Epub 2010 Nov 9.
Wear of polyethylene acetabular cups in patients of total hip arthroplasty is routinely deduced from the penetration of the femoral head into the acetabular liner as observed in the radiographs. However, the linear penetration thus measured represents the cumulative contribution of two components, one due to wear, and the other due to creep or irreversible deformation of the polyethylene structure. The erroneous attribution to wear of the entire penetration displacement of the head in the cup might lead to misinterpretation of the actual performance of acetabular cups. The aim of this study was to quantify the head displacement components due to wear and to creep, as they occur in vivo in acetabular cups, and to relate them to the oxidation state of the material by means of advanced Raman spectroscopy procedures. Throughout the investigation, we compared the behaviors on the molecular scale of acetabular cups subjected to different sterilization methods (i.e., γ-irradiation and ethylene oxide treatment).
在全髋关节置换术患者中，聚乙烯髋臼杯的磨损通常是根据 X 光片中观察到的股骨头对髋臼衬垫的穿透情况来推断的。然而，这种线性穿透所代表的是两个组成部分的累积贡献，一个是由于磨损，另一个是由于聚乙烯结构的蠕变或不可逆变形。将头部在杯中的整个穿透位移错误地归因于磨损，可能会导致对髋臼杯实际性能的错误解读。本研究的目的是量化髋臼杯内发生的磨损和蠕变引起的头部位移分量，并通过先进的拉曼光谱程序将其与材料的氧化状态联系起来。在整个研究过程中，我们比较了不同灭菌方法（γ 辐照和环氧乙烷处理）下髋臼杯在分子尺度上的行为。
