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重症肌无力患者的胸腔镜胸腺切除术数量与胸腺肿瘤胸腔镜切除术的学习曲线之间是否存在关联?

Does a relationship exist between the number of thoracoscopic thymectomies performed and the learning curve for thoracoscopic resection of thymoma in patients with myasthenia gravis?

作者信息

Toker Alper, Erus Suat, Ozkan Berker, Ziyade Sedat, Tanju Serhan

机构信息

Department of Thoracic Surgery, Istanbul University, Istanbul Medical School, Istanbul, Turkey.

出版信息

Interact Cardiovasc Thorac Surg. 2011 Feb;12(2):152-5. doi: 10.1510/icvts.2010.254599. Epub 2010 Nov 9.

DOI:10.1510/icvts.2010.254599
PMID:21068010
Abstract

This study aimed to analyze surgeons' learning curve for thymoma resection with video-assisted thoracoscopic surgery (VATS). Two hundred and eleven myasthenia gravis patients had VATS thymic resections, including 25 patients with a thymoma. Three groups of surgeries, according to the order of operations, were analyzed: Group A comprised the first 70 thymectomies, Group B comprised the second 70 thymectomies, and Group C comprised the final 71 thymectomies. We compared the groups on a set of preoperative (age, gender, body mass index, and Osserman stage), operative (number in each group, size, and Masaoka stage), and postoperative (complications and length of stay) variables. A significant difference was observed in the number of thymoma operations (Group A: four patients, Group B: seven patients, and Group C: 14 patients; P: 0.031) and the duration of operation (Group A: 66 min, Group B: 52 min, and Group C: 48 min; P: 0.024). A strong correlation was found between the duration of operation and order of patients (Pearson r: -0.554, P: 0.000). We recommend the start of a program for the resection of thymoma with VATS after surgical staff have performed 70 VATS thymectomy operations.

摘要

本研究旨在分析外科医生采用电视辅助胸腔镜手术(VATS)切除胸腺瘤的学习曲线。211例重症肌无力患者接受了VATS胸腺切除术,其中25例患有胸腺瘤。根据手术顺序分析了三组手术:A组包括前70例胸腺切除术,B组包括接下来的70例胸腺切除术,C组包括最后71例胸腺切除术。我们比较了三组患者的一系列术前变量(年龄、性别、体重指数和 Osserman 分期)、手术变量(每组手术例数、肿瘤大小和 Masaoka 分期)以及术后变量(并发症和住院时间)。结果发现胸腺瘤手术例数(A组:4例患者,B组:7例患者,C组:14例患者;P值:0.031)和手术时长(A组:66分钟,B组:52分钟,C组:48分钟;P值:0.024)存在显著差异。手术时长与患者手术顺序之间存在强相关性(Pearson相关系数r:-0.554,P值:0.000)。我们建议在手术人员完成70例VATS胸腺切除术后启动VATS切除胸腺瘤的项目。

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