Grollier G, Breut C, Commeau P, Scanu P, Sesboué B, Lamy E, Huret B, Lognoné T, Hédoire F, Bonnefoy L
Service des soins intensifs de cardiologie, CHU Côte de Nacre, Caen.
Arch Mal Coeur Vaiss. 1990 Feb;83(2):159-66.
The results of immediate percutaneous transluminal coronary angioplasty (PTCA) (260 +/- 167 minutes after onset of pain and an average of 56 minutes after thrombolysis) and deferred PTCA (average 9.6 days, range 1 to 30 days after infarction) were compared in 118 consecutive patients with acute myocardial infarction. The overall primary success rate of PTCA was 82.2 per cent; it was higher in those patients undergoing deferred angioplasty (96% vs 78%; p less than 0.05). The primary success rate of immediate PTCA was related to the severity of the stenosis before dilatation: 75 per cent success in occluded compared to 84 per cent in suboccluded vessels (over 90% stenosis) and 100 per cent success in vessels with under 90 per cent stenosis. Eighty one per cent of failed angioplasties occurred in patients with occluded arteries, the majority being left anterior descending (LAD) arteries (71.4%). The incidence of restenosis was 13.4 per cent. This complication was diagnosed at coronary arteriography performed 40 days after PTCA in 1 case, 47 days after PTCA in another case and at the 6 month control in 11 cases. Reocclusion was observed in 21 patients (21.7% of immediate successes). The occlusion was diagnosed at the first control after an average of 8 days in 15 cases. The interval between the onset of pain and thrombolysis and dilatation was significantly longer in the group with reocclusion compared with patients without reocclusion (314 minutes vs 193 minutes for thrombolysis, p less than 0.01; and 356 minutes vs 204 minutes fort PTCA, p less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)
对118例连续的急性心肌梗死患者比较了直接经皮腔内冠状动脉成形术(PTCA)(疼痛发作后260±167分钟,溶栓后平均56分钟)和延迟PTCA(平均9.6天,梗死后1至30天)的结果。PTCA的总体主要成功率为82.2%;接受延迟血管成形术的患者该成功率更高(96%对78%;p<0.05)。直接PTCA的主要成功率与扩张前狭窄的严重程度有关:闭塞血管的成功率为75%,次全闭塞血管(狭窄超过90%)为84%,狭窄低于90%的血管为100%。81%的血管成形术失败发生在动脉闭塞的患者中,大多数为左前降支(LAD)动脉(71.4%)。再狭窄发生率为13.4%。1例患者在PTCA后40天进行冠状动脉造影时诊断出该并发症,另1例在PTCA后47天诊断出,11例在6个月复查时诊断出。21例患者(直接成功患者的21.7%)出现再闭塞。15例患者平均在8天的首次复查时诊断出闭塞。与未发生再闭塞的患者相比,发生再闭塞的患者疼痛发作与溶栓及扩张之间的间隔明显更长(溶栓时为314分钟对193分钟,p<0.01;PTCA时为356分钟对204分钟,p<0.001)。(摘要截短至250字)