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治疗腱病:自体全血和富含血小板的血浆注射有作用吗?

Treatment of tendinopathy: is there a role for autologous whole blood and platelet rich plasma injection?

机构信息

Department of Orthopaedics, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

出版信息

Int J Clin Pract. 2010 Dec;64(13):1813-23. doi: 10.1111/j.1742-1241.2010.02432.x.

Abstract

BACKGROUND

Chronic tendinopathies are a common source of disability and can be recalcitrant to conservative measures, which once exhausted may necessitate operative intervention. Blood and platelets, in particular, are a rich source of factors necessary for tissue healing. Autologous blood injections (ABI) are thought to promote tendon healing, but have been explored clinically in only a few limited studies. However, recently they have attracted media attention in relation to the world of professional athletes and sports-related injuries.

METHOD

We review the evidence base for this technique using the available literature on PubMed.

CONCLUSION

Refractory chronic tendinopathy may be responsive to ABIs, but the data available to date are limited by quality and size of study, as well as length of follow up, and are currently insufficient to recommend this modality for routine clinical use.

摘要

背景

慢性肌腱病是一种常见的致残原因,且对保守治疗措施有抗性,一旦保守治疗措施无效,可能需要手术干预。血液和血小板是组织愈合所需因子的丰富来源。自体血注射(ABI)被认为可以促进肌腱愈合,但在临床上仅在少数有限的研究中进行了探索。然而,最近它们因与职业运动员和与运动相关的损伤相关的世界而受到媒体关注。

方法

我们使用 PubMed 上的现有文献,回顾了该技术的证据基础。

结论

难治性慢性肌腱病可能对 ABI 有反应,但目前可用的数据受到研究质量和大小、随访时间的限制,目前不足以推荐该方法常规用于临床。

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