Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Dig Surg. 2010;27(6):487-91. doi: 10.1159/000318770. Epub 2010 Nov 11.
Several patients with gastroesophageal reflux disease suffer from functional dyspepsia. After laparoscopic Nissen fundoplication, these symptoms persist in a substantial number of patients. We hypothesized that, due to a higher chance of vagal nerve impairment during extensive hernia sac resection and esophageal mobilization, dyspeptic symptoms are more frequent after laparoscopic large hiatal hernia (types II-IV) repair than after primary antireflux surgery.
From January 2003 to December 2007, 60 consecutive patients who primarily underwent an antireflux fundoplication for gastroesophageal reflux disease and 22 consecutive patients who had large hiatal hernia repair with fundoplication for concomitant gastroesophageal reflux disease were included. According to a system combining frequency and severity, patients scored 8 dyspeptic symptoms. Additionally, symptoms presenting preoperatively were scored according to the Visick grading system.
In 43 of the 49 available patients (87.8%) who primarily underwent antireflux surgery and in all 20 available patients who had hiatal hernia repair, preoperative symptoms resolved or improved. Mean symptom scores of all dyspeptic symptoms after surgery were comparable between both cohorts. General quality of life was equal in both cohorts.
After laparoscopic large hiatal hernia repair, dyspeptic symptoms were present in similar frequencies as after primary antireflux surgery.
一些胃食管反流病患者同时患有功能性消化不良。在腹腔镜下进行 Nissen 胃底折叠术(一种抗反流手术)后,这些症状在相当数量的患者中持续存在。我们假设,由于在广泛的疝囊切除和食管游离过程中迷走神经损伤的可能性更高,与原发性抗反流手术相比,腹腔镜下大型食管裂孔疝(II-IV 型)修补术后,消化不良症状更为常见。
从 2003 年 1 月至 2007 年 12 月,我们连续纳入 60 例因胃食管反流病而初次接受抗反流胃底折叠术的患者和 22 例因同时患有胃食管反流病而接受大型食管裂孔疝修补术和胃底折叠术的患者。根据一种结合频率和严重程度的系统,患者对 8 种消化不良症状进行评分。此外,根据 Visick 分级系统对术前症状进行评分。
在 49 例可评估的初次接受抗反流手术的患者中有 43 例(87.8%)和 20 例可评估的接受大型食管裂孔疝修补术的患者中所有 20 例患者中,术前症状缓解或改善。两组患者术后所有消化不良症状的平均症状评分无差异。两组患者的总体生活质量相当。
腹腔镜下大型食管裂孔疝修补术后,消化不良症状的发生频率与初次抗反流手术相似。