相似文献
1
RNA channelling by the eukaryotic exosome.
EMBO Rep. 2010 Dec;11(12):936-42. doi: 10.1038/embor.2010.164. Epub 2010 Nov 12.
2
Poring over exosome structure.
EMBO Rep. 2010 Dec;11(12):900-1. doi: 10.1038/embor.2010.184. Epub 2010 Nov 12.
3
Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex.
Nature. 2013 Mar 7;495(7439):70-5. doi: 10.1038/nature11870. Epub 2013 Feb 3.
4
Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family.
Mol Cell. 2008 Mar 28;29(6):717-28. doi: 10.1016/j.molcel.2008.02.018.
5
Cryo-Electron Microscopy of Endogenous Yeast Exosomes.
Methods Mol Biol. 2020;2062:401-415. doi: 10.1007/978-1-4939-9822-7_19.
6
Reconstitution of S. cerevisiae RNA Exosome Complexes Using Recombinantly Expressed Proteins.
Methods Mol Biol. 2020;2062:427-448. doi: 10.1007/978-1-4939-9822-7_21.
7
Nuclear RNA Exosome at 3.1 Å Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3.
Mol Cell. 2016 Nov 17;64(4):734-745. doi: 10.1016/j.molcel.2016.09.038. Epub 2016 Nov 3.
8
The yeast exosome functions as a macromolecular cage to channel RNA substrates for degradation.
Cell. 2009 Oct 30;139(3):547-59. doi: 10.1016/j.cell.2009.08.042.
9
Nucleolar localization of the yeast RNA exosome subunit Rrp44 hints at early pre-rRNA processing as its main function.
J Biol Chem. 2020 Aug 7;295(32):11195-11213. doi: 10.1074/jbc.RA120.013589. Epub 2020 Jun 17.
10
Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase.
Elife. 2017 Jul 25;6:e29062. doi: 10.7554/eLife.29062.
引用本文的文献
1
EXOSC3 S1-domain variants implicated in PCH1b alter RNA exosome cap subunit abundance and thermal stability disrupting rRNA processing and targeting of AU-rich mRNA.
bioRxiv. 2025 Jun 1:2025.05.31.657176. doi: 10.1101/2025.05.31.657176.
2
RNA compaction and iterative scanning for small RNA targets by the Hfq chaperone.
Nat Commun. 2024 Mar 7;15(1):2069. doi: 10.1038/s41467-024-46316-6.
3
Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol Cell. 2023 Nov 16;83(22):4093-4105.e7. doi: 10.1016/j.molcel.2023.09.037. Epub 2023 Oct 24.
4
MPP6 stimulates both RRP6 and DIS3 to degrade a specified subset of MTR4-sensitive substrates in the human nucleus.
Nucleic Acids Res. 2022 Aug 26;50(15):8779-8806. doi: 10.1093/nar/gkac559.
5
Landscape of functional interactions of human processive ribonucleases revealed by high-throughput siRNA screenings.
iScience. 2021 Aug 27;24(9):103036. doi: 10.1016/j.isci.2021.103036. eCollection 2021 Sep 24.
6
Exosome component 1 cleaves single-stranded DNA and sensitizes human kidney renal clear cell carcinoma cells to poly(ADP-ribose) polymerase inhibitor.
Elife. 2021 Jun 23;10:e69454. doi: 10.7554/eLife.69454.
7
Bi-allelic missense variant, p.Ser35Leu in EXOSC1 is associated with pontocerebellar hypoplasia.
Clin Genet. 2021 Apr;99(4):594-600. doi: 10.1111/cge.13928. Epub 2021 Jan 28.
8
The RNA exosome complex degrades expanded hexanucleotide repeat RNA in C9orf72 FTLD/ALS.
EMBO J. 2020 Oct 1;39(19):e102700. doi: 10.15252/embj.2019102700. Epub 2020 Aug 24.
9
Biallelic variants in the RNA exosome gene EXOSC5 are associated with developmental delays, short stature, cerebellar hypoplasia and motor weakness.
Hum Mol Genet. 2020 Aug 3;29(13):2218-2239. doi: 10.1093/hmg/ddaa108.
10
The RNA Exosome and Human Disease.
Methods Mol Biol. 2020;2062:3-33. doi: 10.1007/978-1-4939-9822-7_1.
本文引用的文献
1
Crystal structure of the S. solfataricus archaeal exosome reveals conformational flexibility in the RNA-binding ring.
PLoS One. 2010 Jan 15;5(1):e8739. doi: 10.1371/journal.pone.0008739.
2
The yeast exosome functions as a macromolecular cage to channel RNA substrates for degradation.
Cell. 2009 Oct 30;139(3):547-59. doi: 10.1016/j.cell.2009.08.042.
3
The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome.
Nucleic Acids Res. 2009 Mar;37(4):1127-40. doi: 10.1093/nar/gkn1020. Epub 2009 Jan 7.
4
The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.
Nat Struct Mol Biol. 2009 Jan;16(1):56-62. doi: 10.1038/nsmb.1528. Epub 2008 Dec 7.
5
Endonucleolytic RNA cleavage by a eukaryotic exosome.
Nature. 2008 Dec 18;456(7224):993-6. doi: 10.1038/nature07480. Epub 2008 Dec 7.
6
Structural organization of the RNA-degrading exosome.
Curr Opin Struct Biol. 2008 Dec;18(6):709-13. doi: 10.1016/j.sbi.2008.10.004. Epub 2008 Nov 13.
7
Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family.
Mol Cell. 2008 Mar 28;29(6):717-28. doi: 10.1016/j.molcel.2008.02.018.
8
Protein structure fitting and refinement guided by cryo-EM density.
Structure. 2008 Feb;16(2):295-307. doi: 10.1016/j.str.2007.11.016.
9
RNA recognition by 3'-to-5' exonucleases: the substrate perspective.
Biochim Biophys Acta. 2008 Apr;1779(4):256-65. doi: 10.1016/j.bbagrm.2007.11.004. Epub 2007 Dec 3.
10
Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing.
Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16844-9. doi: 10.1073/pnas.0705526104. Epub 2007 Oct 17.
Zotero 插件