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肾移植后疱疹病毒感染的临床表现:各种综合征的前瞻性研究

Clinical manifestations of infections with herpesviruses after kidney transplantation: a prospective study of various syndromes.

作者信息

Naraqi S, Jonasson O, Jackson G G, Yamashiroya H M

出版信息

Ann Surg. 1978 Aug;188(2):234-9. doi: 10.1097/00000658-197808000-00017.

Abstract

Herpesviruses infections occur commonly following kidney transplantation and immunosuppression, and contribute substantially to morbidity in the transplant recipient. In this prospective study, stomatitis, mononucleosis, hepatitis, or interstitial pneumonia occurred in 24 of 30 patients (80%) as a result of reactivation of latent herpesvirus infections, but the majority of these syndromes were self-limited and the infections were often asymptomatic. Rejection occurred significantly more frequently in CMV-infected patients, but a distinct causal relationship cannot be deduced.

摘要

肾移植和免疫抑制后常发生疱疹病毒感染,这在很大程度上导致了移植受者的发病。在这项前瞻性研究中,30名患者中有24名(80%)因潜伏性疱疹病毒感染的激活而出现口腔炎、单核细胞增多症、肝炎或间质性肺炎,但这些综合征大多为自限性,且感染通常无症状。巨细胞病毒感染的患者排斥反应明显更频繁发生,但无法推断出明确的因果关系。

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本文引用的文献

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Br Med J. 1972 Dec 2;4(5839):520-2. doi: 10.1136/bmj.4.5839.520.

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