肾移植患者的单纯疱疹性角膜炎
Herpes simplex keratitis in renal transplant patients.
作者信息
Kremer I, Wagner A, Shmuel D, Yussim A, Shapira Z
机构信息
Department of Ophthalmology, Beilinson Medical Center, Petah Tiqva, Israel.
出版信息
Br J Ophthalmol. 1991 Feb;75(2):94-6. doi: 10.1136/bjo.75.2.94.
Abstract
Five out of 430 patients (1.16%) undergoing kidney transplantation developed an atypical clinical picture of herpetic dendritic keratitis within four weeks after surgery. It was manifested by multiple dendrites, located mainly in the corneal periphery or the limbus, developing in relatively uninflamed eyes. The response to acyclovir therapy was prolonged and took at least three weeks. Additionally, subepithelial infiltrates with ultimate scarring developed in all patients. Disciform keratopathy was not found. This clinical course is ascribed to the patients' immunosuppressed state.
摘要
430例接受肾移植的患者中有5例（1.16%）在术后4周内出现了疱疹性树枝状角膜炎的非典型临床表现。其表现为多个树枝状病灶，主要位于角膜周边或角膜缘，在炎症相对不明显的眼中发展。对阿昔洛韦治疗的反应延长，至少需要三周时间。此外，所有患者均出现了上皮下浸润并最终形成瘢痕。未发现盘状角膜病变。这种临床过程归因于患者的免疫抑制状态。
相似文献
1
Herpes simplex keratitis in renal transplant patients.肾移植患者的单纯疱疹性角膜炎
Br J Ophthalmol. 1991 Feb;75(2):94-6. doi: 10.1136/bjo.75.2.94.
2
Herpes simplex keratitis in renal transplant recipients.肾移植受者的单纯疱疹性角膜炎
Can Med Assoc J. 1981 Feb 1;124(3):292-4.
3
Herpes simplex keratitis after cataract surgery.白内障手术后的单纯疱疹性角膜炎
Cornea. 2007 Jun;26(5):615-7. doi: 10.1097/ICO.0b013e318033a708.
4
New onset of herpes simplex virus epithelial keratitis after penetrating keratoplasty.穿透性角膜移植术后新发单纯疱疹病毒上皮性角膜炎
Am J Ophthalmol. 2004 Mar;137(3):415-9. doi: 10.1016/j.ajo.2003.09.057.
5
[Systemic acyclovir therapy in recurrent keratouveitis caused by herpes simplex virus].[全身性阿昔洛韦治疗单纯疱疹病毒引起的复发性角膜葡萄膜炎]
Klin Monbl Augenheilkd. 1984 Dec;185(6):539-42. doi: 10.1055/s-2008-1054691.
6
Acyclovir treatment in stromal herpetic keratitis.基质性疱疹性角膜炎的阿昔洛韦治疗
Doc Ophthalmol. 1983 Dec 15;56(1-2):81-8. doi: 10.1007/BF00154713.
7
Use of Acyclovir in herpes simplex corneal ulcers.阿昔洛韦在单纯疱疹性角膜溃疡中的应用。
Trans Ophthalmol Soc U K (1962). 1981;101(1):6-8.
8
Comparison of the efficacy and toxicity of acyclovir and of adenine arabinoside when combined with dilute betamethasone in herpetic disciform keratitis: preliminary results of a double-blind trial.阿昔洛韦与阿糖腺苷联合稀释倍他米松治疗盘状疱疹性角膜炎的疗效与毒性比较：一项双盲试验的初步结果
Trans Ophthalmol Soc U K (1962). 1983;103 ( Pt 6):597-9.
9
Acyclovir (Zovirax) in herpetic disciform keratitis.阿昔洛韦（无环鸟苷）治疗盘状疱疹性角膜炎。
Br J Ophthalmol. 1983 Feb;67(2):115-8. doi: 10.1136/bjo.67.2.115.
10
A double-blind comparative trial of acyclovir and adenine arabinoside in combination with dilute betamethasone in the management of herpetic disciform keratitis.阿昔洛韦与阿糖腺苷联合稀释倍他米松治疗盘状疱疹性角膜炎的双盲对照试验。
Curr Eye Res. 1987 Jan;6(1):221-4. doi: 10.3109/02713688709020094.
引用本文的文献
1
Herpetic Keratitis Following Treatment of Acute Antibody-Mediated Rejection in a Renal Transplantation Recipient.肾移植受者急性抗体介导排斥反应治疗后发生的疱疹性角膜炎
Cureus. 2024 Jan 5;16(1):e51711. doi: 10.7759/cureus.51711. eCollection 2024 Jan.
2
Corneal Perforation Repair Using a Novel Lyophilized Amniotic Membrane Graft Technique: Plug and Patch.使用新型冻干羊膜移植技术修复角膜穿孔：塞子和补丁。
Am J Case Rep. 2023 Jun 20;24:e939626. doi: 10.12659/AJCR.939626.
3
Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis.单纯疱疹病毒性上皮性角膜炎的抗病毒治疗及其他治疗干预措施。
Cochrane Database Syst Rev. 2015 Jan 9;1(1):CD002898. doi: 10.1002/14651858.CD002898.pub5.
4
Intravenous acyclovir treatment for extensive herpetic keratitis in a liver transplant patient.肝移植患者广泛疱疹性角膜炎的静脉注射阿昔洛韦治疗
Int Ophthalmol. 1997;21(5):265-8. doi: 10.1023/a:1006057204609.
5
Herpes simplex keratitis in renal transplant patients.肾移植患者的单纯疱疹性角膜炎
Br J Ophthalmol. 1991 Nov;75(11):704. doi: 10.1136/bjo.75.11.704.
本文引用的文献
1
Herpes simplex keratitis in renal transplant recipients.肾移植受者的单纯疱疹性角膜炎
Can Med Assoc J. 1981 Feb 1;124(3):292-4.
2
Role of T-lymphocytes in the pathogenesis of herpetic stromal keratitis.T淋巴细胞在疱疹性基质性角膜炎发病机制中的作用。
Invest Ophthalmol Vis Sci. 1984 Aug;25(8):938-44.
3
Association of herpesvirus infections with T-lymphocyte-subset alterations, glomerulopathy, and opportunistic infections after renal transplantation.肾移植后疱疹病毒感染与T淋巴细胞亚群改变、肾小球病及机会性感染的关联
N Engl J Med. 1983 Feb 10;308(6):307-13. doi: 10.1056/NEJM198302103080603.
4
Infections caused by herpes simplex virus in the immunocompromised host: natural history and topical acyclovir therapy.免疫功能低下宿主中单纯疱疹病毒引起的感染：自然病程与局部阿昔洛韦治疗
J Infect Dis. 1984 Sep;150(3):323-9. doi: 10.1093/infdis/150.3.323.
5
Dendritic (herpetic) keratitis. I. Incidence--seasonal variations--recurrence rate--visual impairment--therapy.树枝状（疱疹性）角膜炎。一、发病率——季节变化——复发率——视力损害——治疗
Acta Ophthalmol (Copenh). 1970;48(1):91-107. doi: 10.1111/j.1755-3768.1970.tb06577.x.
6
Herpesviruses in renal transplant patients.肾移植患者中的疱疹病毒
Transplantation. 1973 Nov;16(5):489-95. doi: 10.1097/00007890-197311000-00014.
7
Herpes virus in the lacrimal gland, conjunctiva and cornea of man--a chronic infection.人泪腺、结膜和角膜中的疱疹病毒——一种慢性感染。
Am J Ophthalmol. 1968 Jan;65(1):32-5. doi: 10.1016/0002-9394(68)91024-6.
8
Epidemiological and clinical features of primary herpes simplex virus ocular infection.原发性单纯疱疹病毒眼部感染的流行病学和临床特征
Br J Ophthalmol. 1985 Jan;69(1):2-6. doi: 10.1136/bjo.69.1.2.
9
A comparative study of herpes simplex infections in renal transplant and leukemic patients.肾移植患者和白血病患者单纯疱疹感染的比较研究。
J Infect Dis. 1987 Aug;156(2):280-7. doi: 10.1093/infdis/156.2.280.
10
Viral infections in kidney transplant patients immunosuppressed with cyclosporine.接受环孢素免疫抑制治疗的肾移植患者中的病毒感染。
Transplant Proc. 1987 Feb;19(1 Pt 3):2142-9.
Zotero 插件