Mattioli-Belmonte Monica, Orciani Monia, Ferretti Concetta, Orsini Giovanna, De Giglio Elvira, Di Primio Roberto
Sezione di Istologia ed Embriologia Umana, Dipartimento di Patologia Molecolare e Terapie Innovative.
Ital J Anat Embryol. 2010;115(1-2):127-33.
Researchers are testing different treatments to induce modifications in both chemical composition and topography of implant surface, with the aim to ameliorate bone-to-implant contacts and hence improve osseointegration processes and biomechanical properties in the short and long-term. Aim of the present research was the evaluation of MG63 osteoblast-like cells behaviour on polymeric coatings, electrosynthesized on titanium substrates, differently modified in order to improve implant performances both in terms of osseointegration and infection prevention. Cell viability data and scanning electron microscopy morphological observations were consistent with a good compatibility of modified electrosynthesized coatings and suggest the use of this procedure to produce new bioactive titanium coatings for implant surgery.
研究人员正在测试不同的处理方法,以诱导种植体表面化学成分和形貌的改变,目的是改善骨与种植体的接触,从而在短期和长期内改善骨整合过程及生物力学性能。本研究的目的是评估MG63成骨样细胞在钛基底上通过电合成制备的聚合物涂层上的行为,这些涂层经过不同的改性,以在骨整合和预防感染方面改善种植体性能。细胞活力数据和扫描电子显微镜形态学观察结果表明,改性电合成涂层具有良好的相容性,并表明可利用该方法生产用于种植手术的新型生物活性钛涂层。