Kudsk K A, Campbell S M, O'Brien T, Fuller R
Nutr Clin Pract. 1990 Feb;5(1):14-7. doi: 10.1177/011542659000500114.
Some surgeons avoid placing a jejunostomy in patients with complications, fearing either exacerbation of the disease during enteral feedings or complications from the jejunostomies. Eleven patients with hemorrhagic pancreatitis (four), pancreatic abscess (five), or infected pseudocyst (two) underwent placements of needle (five) or Red Robinson (six) jejunal catheters during laparotomy. Five patients had been given 30.8 +/- 16 liters of TPN over 25 +/- 12 days preoperatively. Only two patients received TPN postoperatively because of progressive sepsis with enteral intolerance to feedings. One of these patients developed a jejunal leak near the placement of the Red Robinson catheter. Both patients died of complications from their pancreatic disease. The remaining nine patients received 35.6 +/- 8.6 liters of enteral feedings over 31 +/- 6.8 days before resuming oral intake. Glucosuria and hyperglycemia were common, but easily managed. No catheters were lost, and diarrhea necessitating slowing and diluting the diet was unusual after the first week. Enteral feeding did not elevate amylase values. Therefore, jejunal feedings can be given safely in patients with severe acute pancreatic disease to provide prolonged nutrition without aggravating the disease.
一些外科医生避免给有并发症的患者放置空肠造口管,担心肠内喂养期间疾病恶化或空肠造口管引发并发症。11例出血性胰腺炎患者(4例)、胰腺脓肿患者(5例)或感染性假性囊肿患者(2例)在剖腹手术期间接受了针式(5例)或雷德·罗宾逊式(6例)空肠导管置入。5例患者术前在25±12天内接受了30.8±16升的全胃肠外营养(TPN)。术后仅2例患者因进行性脓毒症且对肠内喂养不耐受而接受TPN。其中1例患者在雷德·罗宾逊导管置入部位附近发生空肠渗漏。这2例患者均死于胰腺疾病并发症。其余9例患者在恢复经口进食前的31±6.8天内接受了35.6±8.6升的肠内喂养。糖尿和高血糖很常见,但易于处理。没有导管丢失,第一周后因腹泻需要减慢饮食速度并稀释饮食的情况并不常见。肠内喂养并未升高淀粉酶值。因此,对于重症急性胰腺疾病患者,可以安全地给予空肠喂养,以提供长期营养而不加重病情。